FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978397854> ?p ?o ?g. }

• W1978397854 endingPage "543" @default.
• W1978397854 startingPage "538" @default.
• W1978397854 abstract "Experimental models to study cerebrovascular malformations are limited therefore we used the neonatal rodent retina as a model to study cerebral angiogenesis.We performed a gene expression analysis to define temporal changes in the expression of 96 angiogenesis-related genes during retinal vascularization.A total of 72 retinas from 36 newborn C57BL/6 mice were used. Sets of neonatal mouse retinas were surgically isolated by 2-day intervals starting from postnatal day 0 to day 20 and at the 32nd day (representing adult retinas). For each of these 12 time points in the postnatal developmental period of mouse retinas, separate sets of 6 retinas from 3 mice were pooled, and their RNA was hybridized to an angiogenesis-specific gene array. Temporal expression patterns of each of the 96 angiogenesis-related genes were analyzed. For confirmation, vascular endothelial growth factor protein expression was also studied by immunohistochemistry.Twenty-two of the 96 genes analyzed displayed a significantly different temporal expression profile, and the rest exhibited a static expression, as compared to the human glyceraldehyde-3-phosphate dehydrogenase gene. Among these genes, the temporal pattern of expression was variable, but peaks were seen mostly on days 8, 10, 12, and 16. This timing corresponds well to morphologic changes that occur in the retina during different stages of angiogenesis.The neonatal rodent retina, which has a cellular architecture similar to that of the brain, has active and quantifiable angiogenic activity during the neonatal period and can be used as a simple and convenient model to study cerebral angiogenesis." @default.
• W1978397854 created "2016-06-24" @default.
• W1978397854 creator A5010548095 @default.
• W1978397854 creator A5013113053 @default.
• W1978397854 creator A5016205178 @default.
• W1978397854 creator A5062571375 @default.
• W1978397854 creator A5067820753 @default.
• W1978397854 creator A5089452299 @default.
• W1978397854 date "2010-03-01" @default.
• W1978397854 modified "2023-10-16" @default.
• W1978397854 title "Temporal Expression of Angiogenesis-Related Genes in Developing Neonatal Rodent Retina" @default.
• W1978397854 cites W1495287184 @default.
• W1978397854 cites W1576609386 @default.
• W1978397854 cites W1975744936 @default.
• W1978397854 cites W1979191515 @default.
• W1978397854 cites W1992159395 @default.
• W1978397854 cites W2008433684 @default.
• W1978397854 cites W2009248197 @default.
• W1978397854 cites W2010017413 @default.
• W1978397854 cites W2016140581 @default.
• W1978397854 cites W2021659118 @default.
• W1978397854 cites W2031688559 @default.
• W1978397854 cites W2032024195 @default.
• W1978397854 cites W2033585891 @default.
• W1978397854 cites W2040123890 @default.
• W1978397854 cites W2040965438 @default.
• W1978397854 cites W2053052279 @default.
• W1978397854 cites W2058217379 @default.
• W1978397854 cites W2076654705 @default.
• W1978397854 cites W2099596147 @default.
• W1978397854 cites W2100155631 @default.
• W1978397854 cites W2100979164 @default.
• W1978397854 cites W2144847798 @default.
• W1978397854 cites W2159039246 @default.
• W1978397854 cites W2168558463 @default.
• W1978397854 cites W2171333970 @default.
• W1978397854 doi "https://doi.org/10.1227/01.neu.0000365615.24973.26" @default.
• W1978397854 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20173549" @default.
• W1978397854 hasPublicationYear "2010" @default.
• W1978397854 type Work @default.
• W1978397854 sameAs 1978397854 @default.
• W1978397854 citedByCount "6" @default.
• W1978397854 countsByYear W19783978542012 @default.
• W1978397854 countsByYear W19783978542013 @default.
• W1978397854 countsByYear W19783978542014 @default.
• W1978397854 countsByYear W19783978542021 @default.
• W1978397854 crossrefType "journal-article" @default.
• W1978397854 hasAuthorship W1978397854A5010548095 @default.
• W1978397854 hasAuthorship W1978397854A5013113053 @default.
• W1978397854 hasAuthorship W1978397854A5016205178 @default.
• W1978397854 hasAuthorship W1978397854A5062571375 @default.
• W1978397854 hasAuthorship W1978397854A5067820753 @default.
• W1978397854 hasAuthorship W1978397854A5089452299 @default.
• W1978397854 hasConcept C104317684 @default.
• W1978397854 hasConcept C126322002 @default.
• W1978397854 hasConcept C142724271 @default.
• W1978397854 hasConcept C146285616 @default.
• W1978397854 hasConcept C150194340 @default.
• W1978397854 hasConcept C167734588 @default.
• W1978397854 hasConcept C169760540 @default.
• W1978397854 hasConcept C2777025900 @default.
• W1978397854 hasConcept C2777093970 @default.
• W1978397854 hasConcept C2780394083 @default.
• W1978397854 hasConcept C54355233 @default.
• W1978397854 hasConcept C71924100 @default.
• W1978397854 hasConcept C86803240 @default.
• W1978397854 hasConceptScore W1978397854C104317684 @default.
• W1978397854 hasConceptScore W1978397854C126322002 @default.
• W1978397854 hasConceptScore W1978397854C142724271 @default.
• W1978397854 hasConceptScore W1978397854C146285616 @default.
• W1978397854 hasConceptScore W1978397854C150194340 @default.
• W1978397854 hasConceptScore W1978397854C167734588 @default.
• W1978397854 hasConceptScore W1978397854C169760540 @default.
• W1978397854 hasConceptScore W1978397854C2777025900 @default.
• W1978397854 hasConceptScore W1978397854C2777093970 @default.
• W1978397854 hasConceptScore W1978397854C2780394083 @default.
• W1978397854 hasConceptScore W1978397854C54355233 @default.
• W1978397854 hasConceptScore W1978397854C71924100 @default.
• W1978397854 hasConceptScore W1978397854C86803240 @default.
• W1978397854 hasIssue "3" @default.
• W1978397854 hasLocation W19783978541 @default.
• W1978397854 hasLocation W19783978542 @default.
• W1978397854 hasOpenAccess W1978397854 @default.
• W1978397854 hasPrimaryLocation W19783978541 @default.
• W1978397854 hasRelatedWork W1974165456 @default.
• W1978397854 hasRelatedWork W2009966535 @default.
• W1978397854 hasRelatedWork W2054726204 @default.
• W1978397854 hasRelatedWork W2054830668 @default.
• W1978397854 hasRelatedWork W2093451285 @default.
• W1978397854 hasRelatedWork W2107292539 @default.
• W1978397854 hasRelatedWork W2351853356 @default.
• W1978397854 hasRelatedWork W2764060760 @default.
• W1978397854 hasRelatedWork W3158617048 @default.
• W1978397854 hasRelatedWork W4319660887 @default.
• W1978397854 hasVolume "66" @default.
• W1978397854 isParatext "false" @default.
• W1978397854 isRetracted "false" @default.
• W1978397854 magId "1978397854" @default.

• next