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• W1978404153 abstract "Perception of olfactory stimuli is mediated by distinct populations of olfactory sensory neurons, each with a characteristic set of morphological as well as functional parameters. Beyond two large populations of ciliated and microvillous neurons, a third population, crypt neurons, has been identified in teleost and cartilaginous fishes. We report here a novel, fourth olfactory sensory neuron population in zebrafish, which we named kappe neurons for their characteristic shape. Kappe neurons are identified by their Go-like immunoreactivity and show a distinct spatial distribution within the olfactory epithelium, similar to, but significantly different from that of crypt neurons. Furthermore, kappe neurons project to a single identified target glomerulus within the olfactory bulb, mdg5 of the mediodorsal cluster, whereas crypt neurons are known to project exclusively to the mdg2 glomerulus. Kappe neurons are negative for established markers of ciliated, microvillous and crypt neurons, but appear to have microvilli. Kappe neurons constitute the fourth type of olfactory sensory neurons reported in teleost fishes and their existence suggests that encoding of olfactory stimuli may require a higher complexity than hitherto assumed already in the peripheral olfactory system." @default.
• W1978404153 created "2016-06-24" @default.
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• W1978404153 date "2014-02-10" @default.
• W1978404153 modified "2023-10-11" @default.
• W1978404153 title "Kappe neurons, a novel population of olfactory sensory neurons" @default.
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• W1978404153 doi "https://doi.org/10.1038/srep04037" @default.
• W1978404153 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3918911" @default.
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