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- W1978424789 abstract "A complex containing the Thy-1 (θ) antigen has been isolated from the surface of murine thymocytes and T cells by cell surface radioiodination, lysis by freezing and thawing, and immunoprecipitation. The specificity of the immunoprecipitation was firmly established using both congenic and noncongenic anti-Thy-1 sera and thymocytes from congenic and noncongenic mice. Unlike cell surface Ig and the TL and H-2 alloantigens, the antigenicity of Thy-1 was abolished by treatment with nonionic detergent. Thy-1 was localized exclusively in a complex of cell surface molecules which has a density lower than that of protein. Moreover, Thy-1 could be readily labeled by incubating thymocytes with [3H]galactose, but not 3H-labeled amino acids. These observations suggest that the antigenicity of Thy-1 may reside in a glycolipid." @default.
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- W1978424789 date "1973-07-01" @default.
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- W1978424789 title "Isolation and characterization of a molecular complex containing thy-1 antigen from the surface of murine thymocytes and t cells" @default.
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- W1978424789 doi "https://doi.org/10.1002/eji.1830030714" @default.
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