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• W1978442261 abstract "Corynebacterium glutamicum is one of the best studied organisms of the high G+C branch of Gram-positive bacteria and an emerging model system for the suborder Corynebacterineae. To gain insights into the regulatory gene composition and architecture of the transcriptional regulatory network of C. glutamicum, components of the transcriptional regulatory repertoire were intensively studied by many scientific groups in recent years. In this mini-review, we summarize the present knowledge about the deduced transcriptional regulatory repertoire of C. glutamicum and the current status of transcriptional regulatory network reconstruction with regard to the genome-wide detection of transcriptional regulations, coregulatory interactions and hierarchical cross-regulations. Moreover, we provide an overview of those regulators and their transcriptional regulations controlling genes involved in the conversion of the carbon sources glucose, fructose and sucrose into the industrially relevant products l-lysine and l-glutamate. This data will contribute to our understanding of l-lysine and l-glutamate production by C. glutamicum from the perspective of systems biology and may provide the basis for computational modeling of the respective biotechnologically important metabolic pathways." @default.
• W1978442261 created "2016-06-24" @default.
• W1978442261 creator A5006110463 @default.
• W1978442261 creator A5063562401 @default.
• W1978442261 creator A5069682981 @default.
• W1978442261 creator A5082682293 @default.
• W1978442261 date "2010-09-01" @default.
• W1978442261 modified "2023-09-27" @default.
• W1978442261 title "The transcriptional regulatory repertoire of Corynebacterium glutamicum: Reconstruction of the network controlling pathways involved in lysine and glutamate production" @default.
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• W1978442261 doi "https://doi.org/10.1016/j.jbiotec.2009.12.004" @default.
• W1978442261 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19963020" @default.
• W1978442261 hasPublicationYear "2010" @default.
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