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- W1978474423 abstract "Alkylation of dithymidine phosphorothioate and phosphorodithioate with various iodoalkyl acylates afforded the corresponding uncharged S-alkyl phosphoromono- and di-thioates respectively. Upon incubation of these triesters in CEM cell extracts, the bioreversible alkyl acylate masking groups were selectively and rapidly removed by carboxyesterases present in the milieu, yielding the starting dinucleoside diesters." @default.
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- W1978474423 date "1995-03-01" @default.
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- W1978474423 title "The prooligonucleotide approach. I: Esterase-mediated reversibility of dithymidine S-alkyl-phosphorothiolates to dithymidine phosphorothioates" @default.
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- W1978474423 doi "https://doi.org/10.1016/0960-894x(95)00074-4" @default.
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