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- W1978475492 abstract "Sixty-four representative strains of Vibrio cholerae O139 were analyzed, to re-examine the origin of this serogroup. Ribotyping differentiated the strains into 3 HindIII and 7 BglI ribotypes. One HindIII and 5 BglI ribotypes were shared by all toxigenic O139 strains. Of 6 nontoxigenic O139 strains, 3 shared ribotypes with the toxigenic strains, carried genes encoding toxin coregulated pilus, and were susceptible to the cholera toxin-converting bacteriophage CTXPhi. The remaining 3 strains belonged to 2 different ribotypes distinct from toxigenic O139 strains and were resistant to CTXPhi and JA-1, an O139-specific lytic bacteriophage. Polymerase chain reaction amplicons corresponding to the gmhD gene carried by these 3 strains also differed from those of the toxigenic O139 strains but were identical to those of 15 environmental non-O1-non-O139 strains. Thus, the O139 antigen is present in different lineages, and this serogroup appears to comprise epidemic and nonepidemic strains derived separately from different progenitors." @default.
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- W1978475492 date "2000-10-01" @default.
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- W1978475492 title "The O139 Serogroup of<i>Vibrio cholerae</i>Comprises Diverse Clones of Epidemic and Nonepidemic Strains Derived from Multiple<i>V. cholerae</i>O1 or Non‐O1 Progenitors" @default.
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- W1978475492 doi "https://doi.org/10.1086/315807" @default.
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