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• W1978476682 endingPage "2232" @default.
• W1978476682 startingPage "2228" @default.
• W1978476682 abstract "When we fall asleep, consciousness fades yet the brain remains active. Why is this so? To investigate whether changes in cortical information transmission play a role, we used transcranial magnetic stimulation together with high-density electroencephalography and asked how the activation of one cortical area (the premotor area) is transmitted to the rest of the brain. During quiet wakefulness, an initial response (∼15 milliseconds) at the stimulation site was followed by a sequence of waves that moved to connected cortical areas several centimeters away. During non–rapid eye movement sleep, the initial response was stronger but was rapidly extinguished and did not propagate beyond the stimulation site. Thus, the fading of consciousness during certain stages of sleep may be related to a breakdown in cortical effective connectivity." @default.
• W1978476682 created "2016-06-24" @default.
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• W1978476682 date "2005-09-30" @default.
• W1978476682 modified "2023-10-04" @default.
• W1978476682 title "Breakdown of Cortical Effective Connectivity During Sleep" @default.
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• W1978476682 doi "https://doi.org/10.1126/science.1117256" @default.
• W1978476682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16195466" @default.
• W1978476682 hasPublicationYear "2005" @default.
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