FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978481506> ?p ?o ?g. }

• W1978481506 endingPage "411" @default.
• W1978481506 startingPage "403" @default.
• W1978481506 abstract "Background Atrial fibrillation (AF) is the most common arrhythmia and increases cardiovascular risk in hypertensive patients. Therefore, in the Valsartan Antihypertensive Long-term Use Evaluation (VALUE) a prespecified objective was to compare the effects of valsartan and amlodipine on new-onset AF. Methods A total of 15 245 hypertensive patients at high cardiovascular risk received valsartan 80–160 mg/day or amlodipine 5–10 mg/day combined with additional antihypertensive agents. Electrocardiograms were obtained every year and analyzed centrally for evidence of left ventricular hypertrophy and new-onset AF. Results At baseline, AF was diagnosed in 2.6% of 7649 valsartan recipients and 2.6% of 7596 amlodipine recipients. During antihypertensive treatment the incidence of at least one documented occurrence of new-onset AF was 3.67% with valsartan and 4.34% with amlodipine {unadjusted hazard ratio 0.843, [95% confidence interval (CI): 0.713, 0.997], P = 0.0455}. The incidence of persistent AF was 1.35% with valsartan and 1.97% with amlodipine [unadjusted hazard ratio 0.683 (95% CI: 0.525, 0.889), P = 0.0046]. Conclusions Valsartan-based treatment reduced the development of new-onset AF, particularly sustained AF in hypertensive patients, compared with amlodipine-based therapy. These findings suggest that angiotensin II receptor blockers may result in greater benefits than calcium antagonists in hypertensive patients at risk of new-onset AF." @default.
• W1978481506 created "2016-06-24" @default.
• W1978481506 creator A5042107498 @default.
• W1978481506 creator A5049235067 @default.
• W1978481506 creator A5052937002 @default.
• W1978481506 creator A5065577595 @default.
• W1978481506 creator A5087577272 @default.
• W1978481506 creator A5087708317 @default.
• W1978481506 date "2008-03-01" @default.
• W1978481506 modified "2023-10-13" @default.
• W1978481506 title "Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: the VALUE trial" @default.
• W1978481506 cites W164006490 @default.
• W1978481506 cites W1985550740 @default.
• W1978481506 cites W2023844858 @default.
• W1978481506 cites W2036225612 @default.
• W1978481506 cites W2036605610 @default.
• W1978481506 cites W2056473894 @default.
• W1978481506 cites W2060171803 @default.
• W1978481506 cites W2081957965 @default.
• W1978481506 cites W2089623059 @default.
• W1978481506 cites W2089940123 @default.
• W1978481506 cites W2097546089 @default.
• W1978481506 cites W2102036115 @default.
• W1978481506 cites W2102979143 @default.
• W1978481506 cites W2110642473 @default.
• W1978481506 cites W2111995867 @default.
• W1978481506 cites W2116966911 @default.
• W1978481506 cites W2132458997 @default.
• W1978481506 cites W2136442308 @default.
• W1978481506 cites W2139805666 @default.
• W1978481506 cites W2147918774 @default.
• W1978481506 cites W2148311100 @default.
• W1978481506 cites W2150174446 @default.
• W1978481506 cites W2151074096 @default.
• W1978481506 cites W2152043519 @default.
• W1978481506 cites W2157429813 @default.
• W1978481506 cites W2157870057 @default.
• W1978481506 cites W2160578938 @default.
• W1978481506 cites W2172032309 @default.
• W1978481506 cites W2614763070 @default.
• W1978481506 doi "https://doi.org/10.1097/hjh.0b013e3282f35c67" @default.
• W1978481506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18300848" @default.
• W1978481506 hasPublicationYear "2008" @default.
• W1978481506 type Work @default.
• W1978481506 sameAs 1978481506 @default.
• W1978481506 citedByCount "203" @default.
• W1978481506 countsByYear W19784815062012 @default.
• W1978481506 countsByYear W19784815062013 @default.
• W1978481506 countsByYear W19784815062014 @default.
• W1978481506 countsByYear W19784815062015 @default.
• W1978481506 countsByYear W19784815062016 @default.
• W1978481506 countsByYear W19784815062017 @default.
• W1978481506 countsByYear W19784815062018 @default.
• W1978481506 countsByYear W19784815062019 @default.
• W1978481506 countsByYear W19784815062020 @default.
• W1978481506 countsByYear W19784815062021 @default.
• W1978481506 countsByYear W19784815062022 @default.
• W1978481506 countsByYear W19784815062023 @default.
• W1978481506 crossrefType "journal-article" @default.
• W1978481506 hasAuthorship W1978481506A5042107498 @default.
• W1978481506 hasAuthorship W1978481506A5049235067 @default.
• W1978481506 hasAuthorship W1978481506A5052937002 @default.
• W1978481506 hasAuthorship W1978481506A5065577595 @default.
• W1978481506 hasAuthorship W1978481506A5087577272 @default.
• W1978481506 hasAuthorship W1978481506A5087708317 @default.
• W1978481506 hasConcept C104849204 @default.
• W1978481506 hasConcept C120665830 @default.
• W1978481506 hasConcept C121332964 @default.
• W1978481506 hasConcept C126322002 @default.
• W1978481506 hasConcept C164705383 @default.
• W1978481506 hasConcept C207103383 @default.
• W1978481506 hasConcept C2777387769 @default.
• W1978481506 hasConcept C2779161974 @default.
• W1978481506 hasConcept C2779646130 @default.
• W1978481506 hasConcept C2908929049 @default.
• W1978481506 hasConcept C44249647 @default.
• W1978481506 hasConcept C61511704 @default.
• W1978481506 hasConcept C71924100 @default.
• W1978481506 hasConcept C84393581 @default.
• W1978481506 hasConceptScore W1978481506C104849204 @default.
• W1978481506 hasConceptScore W1978481506C120665830 @default.
• W1978481506 hasConceptScore W1978481506C121332964 @default.
• W1978481506 hasConceptScore W1978481506C126322002 @default.
• W1978481506 hasConceptScore W1978481506C164705383 @default.
• W1978481506 hasConceptScore W1978481506C207103383 @default.
• W1978481506 hasConceptScore W1978481506C2777387769 @default.
• W1978481506 hasConceptScore W1978481506C2779161974 @default.
• W1978481506 hasConceptScore W1978481506C2779646130 @default.
• W1978481506 hasConceptScore W1978481506C2908929049 @default.
• W1978481506 hasConceptScore W1978481506C44249647 @default.
• W1978481506 hasConceptScore W1978481506C61511704 @default.
• W1978481506 hasConceptScore W1978481506C71924100 @default.
• W1978481506 hasConceptScore W1978481506C84393581 @default.
• W1978481506 hasIssue "3" @default.
• W1978481506 hasLocation W19784815061 @default.
• W1978481506 hasLocation W19784815062 @default.
• W1978481506 hasOpenAccess W1978481506 @default.
• W1978481506 hasPrimaryLocation W19784815061 @default.

• next