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- W1978487376 abstract "To determine the effect of prenatal genetic counseling on women's decisions regarding first trimester screening versus invasive diagnostic testing. Pregnant women referred for routine prenatal counseling in the first trimester at the Lucile Packard Children's' Hospital (Stanford University) Perinatal Diagnostic Center were offered enrollment in the study. Enrolled women were mailed questionnaires prior to genetic counseling to assess their intentions to undergo first trimester screening and/or invasive diagnostic testing. Participants then underwent group and individual counseling with genetic counselors, which included education regarding first trimester screening versus invasive testing options. Data on testing choices were collected, and the effect of genetic counseling on choices was assessed. 155 women were enrolled. Prior to genetic counseling, 142 (92%) women stated they wanted definitive information regarding presence of a genetic abnormality, and 19 (12%) planned to undergo invasive diagnostic testing. After genetic counseling, 17 (89%) of the 19 who planned an invasive procedure opted for non-invasive screening instead. 148 women who planned to undergo first trimester screening proceeded with screening following counseling. First trimester genetic counseling altered patients' preliminary plans for invasive diagnostic testing but not for non-invasive screening. Most patients indicated they would like definitive genetic information but only a minority elected invasive diagnostic testing without prior screening. Genetic counseling, or patient education, appears to be an important component of first trimester prenatal testing." @default.
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- W1978487376 date "2009-12-01" @default.
- W1978487376 modified "2023-10-16" @default.
- W1978487376 title "699: First trimester screening versus diagnostic testing; how important is prenatal counseling in the decision-making process?" @default.
- W1978487376 doi "https://doi.org/10.1016/j.ajog.2009.10.716" @default.
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