FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978488098> ?p ?o ?g. }

• W1978488098 endingPage "39" @default.
• W1978488098 startingPage "23" @default.
• W1978488098 abstract "Choline acetyltransferase (ChAT) and vesicular acetylcholine transporter (VAChT) are proteins that are required for cholinergic neurotransmission. Present knowledge concerning the organization of cholinergic structures has been derived primarily from immunohistochemistry for ChAT. In the present study, we investigated the distribution of mRNAs and the corresponding proteins for ChAT and VAChT by in situ hybridization histochemistry and immunohistochemistry. The patterns of distribution of perikarya containing ChAT mRNA, ChAT protein, VAChT mRNA and VAChT protein were similar in most regions, and co-localization in the same neuron of mRNAs for ChAT and VAChT, that of ChAT mRNA and ChAT protein, and that of VAChT mRNA and VAChT protein were demonstrated. However, in the cerebral cortex and hypothalamus, ChAT-immunoreactive perikarya were present, but they did not contain mRNAs for ChAT and VAChT, and VAChT protein. On the other hand, in the cerebellum, Purkinje cell bodies contained VAChT mRNA and VAChT protein, but they did not contain either ChAT mRNA or ChAT protein. Axon bundles were clearly revealed by immunohistochemistry for ChAT, but they were not detected by that for VAChT. Both ChAT and VAChT antibodies revealed preterminal axons and terminal-like structures. In the forebrain, they were present in the olfactory bulb, nucleus of the lateral olfactory tract, olfactory tubercle, lateral septal nucleus, amygdala, hippocampus, neocortex, caudate-putamen, thalamus and median eminence of the hypothalamus. In the brainstem, they were localized in the superior colliculus, interpeduncular nucleus and some cranial nerve motor nuclei, and further in the ventral horn of the spinal cord. These results indicate strongly that ChAT and VAChT are expressed in most of the cholinergic neurons, and that immunohistochemistry for VAChT is as useful to detect cholinergic terminal fields as that for ChAT." @default.
• W1978488098 created "2016-06-24" @default.
• W1978488098 creator A5032867177 @default.
• W1978488098 creator A5056941399 @default.
• W1978488098 creator A5082633209 @default.
• W1978488098 creator A5091136427 @default.
• W1978488098 date "1997-06-01" @default.
• W1978488098 modified "2023-10-18" @default.
• W1978488098 title "Localization of two cholinergic markers, choline acetyltransferase and vesicular acetylcholine transporter in the central nervous system of the rat: in situ hybridization histochemistry and immunohistochemistry" @default.
• W1978488098 cites W105402577 @default.
• W1978488098 cites W1544919124 @default.
• W1978488098 cites W1560799253 @default.
• W1978488098 cites W1601928222 @default.
• W1978488098 cites W1935132610 @default.
• W1978488098 cites W1964316337 @default.
• W1978488098 cites W1967069646 @default.
• W1978488098 cites W1971434876 @default.
• W1978488098 cites W1978298955 @default.
• W1978488098 cites W1983923023 @default.
• W1978488098 cites W1990315746 @default.
• W1978488098 cites W1997590875 @default.
• W1978488098 cites W2005601991 @default.
• W1978488098 cites W2013529541 @default.
• W1978488098 cites W2014198387 @default.
• W1978488098 cites W2018026722 @default.
• W1978488098 cites W2020664594 @default.
• W1978488098 cites W2022567711 @default.
• W1978488098 cites W2033995553 @default.
• W1978488098 cites W2035963056 @default.
• W1978488098 cites W2038855142 @default.
• W1978488098 cites W2040095321 @default.
• W1978488098 cites W2050164747 @default.
• W1978488098 cites W2064660388 @default.
• W1978488098 cites W2065925848 @default.
• W1978488098 cites W2066497322 @default.
• W1978488098 cites W2067627391 @default.
• W1978488098 cites W2070352390 @default.
• W1978488098 cites W2074260855 @default.
• W1978488098 cites W2076636373 @default.
• W1978488098 cites W2082769538 @default.
• W1978488098 cites W2084621470 @default.
• W1978488098 cites W2088092784 @default.
• W1978488098 cites W2090093798 @default.
• W1978488098 cites W2100837269 @default.
• W1978488098 cites W2101108802 @default.
• W1978488098 cites W2104831013 @default.
• W1978488098 cites W2112982765 @default.
• W1978488098 cites W2121405720 @default.
• W1978488098 cites W2133003390 @default.
• W1978488098 cites W2137221134 @default.
• W1978488098 cites W995713276 @default.
• W1978488098 cites W2489024985 @default.
• W1978488098 doi "https://doi.org/10.1016/s0891-0618(97)00021-5" @default.
• W1978488098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9271193" @default.
• W1978488098 hasPublicationYear "1997" @default.
• W1978488098 type Work @default.
• W1978488098 sameAs 1978488098 @default.
• W1978488098 citedByCount "208" @default.
• W1978488098 countsByYear W19784880982012 @default.
• W1978488098 countsByYear W19784880982013 @default.
• W1978488098 countsByYear W19784880982014 @default.
• W1978488098 countsByYear W19784880982015 @default.
• W1978488098 countsByYear W19784880982016 @default.
• W1978488098 countsByYear W19784880982017 @default.
• W1978488098 countsByYear W19784880982018 @default.
• W1978488098 countsByYear W19784880982019 @default.
• W1978488098 countsByYear W19784880982020 @default.
• W1978488098 countsByYear W19784880982021 @default.
• W1978488098 countsByYear W19784880982022 @default.
• W1978488098 countsByYear W19784880982023 @default.
• W1978488098 crossrefType "journal-article" @default.
• W1978488098 hasAuthorship W1978488098A5032867177 @default.
• W1978488098 hasAuthorship W1978488098A5056941399 @default.
• W1978488098 hasAuthorship W1978488098A5082633209 @default.
• W1978488098 hasAuthorship W1978488098A5091136427 @default.
• W1978488098 hasConcept C104317684 @default.
• W1978488098 hasConcept C104966671 @default.
• W1978488098 hasConcept C105580179 @default.
• W1978488098 hasConcept C169760540 @default.
• W1978488098 hasConcept C198399640 @default.
• W1978488098 hasConcept C22885893 @default.
• W1978488098 hasConcept C2776287375 @default.
• W1978488098 hasConcept C2777731756 @default.
• W1978488098 hasConcept C2778205193 @default.
• W1978488098 hasConcept C2780496858 @default.
• W1978488098 hasConcept C44107871 @default.
• W1978488098 hasConcept C529278444 @default.
• W1978488098 hasConcept C552161191 @default.
• W1978488098 hasConcept C55493867 @default.
• W1978488098 hasConcept C81439078 @default.
• W1978488098 hasConcept C86803240 @default.
• W1978488098 hasConceptScore W1978488098C104317684 @default.
• W1978488098 hasConceptScore W1978488098C104966671 @default.
• W1978488098 hasConceptScore W1978488098C105580179 @default.
• W1978488098 hasConceptScore W1978488098C169760540 @default.
• W1978488098 hasConceptScore W1978488098C198399640 @default.
• W1978488098 hasConceptScore W1978488098C22885893 @default.
• W1978488098 hasConceptScore W1978488098C2776287375 @default.

• next