Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978496745> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1978496745 endingPage "370" @default.
- W1978496745 startingPage "363" @default.
- W1978496745 abstract "RNA initiation by Qβ replicase directed by the short-sequence CCA at the 3′-end of all RNAs amplified by this enzyme has been studied. Most CCA repeats in an RNA consisting of 12 CCAs serve as independent sites of de novo RNA initiation, with initiation occurring opposite the 3′-C residue of each CCA. Qβ replicase is thus capable of internal initiation remote from the 3′-end, although predominant initiation occurs close to the 3′-end. The precise 3′-terminal sequence in (CCA)n-containing RNAs influences the number and position of active initiation sites near the 3′-terminus. C residues are required at the initiation site, whereas the position of purines (especially A residues) influences the selection of initiation sites. The template activity of (CCA)n RNAs is positively correlated with the number of CCA repeats. Three CCA repeats added to the 3′-end of a nontemplate 83-nt RNA are sufficient to activate transcription by Qβ replicase. These experiments show that CCA boxes can act as strong initiation sites in the absence of specific cis-acting signals derived from Qβ RNA, although the efficiency of initiation is modulated by surrounding sequence." @default.
- W1978496745 created "2016-06-24" @default.
- W1978496745 creator A5010610734 @default.
- W1978496745 creator A5046937914 @default.
- W1978496745 date "2000-06-01" @default.
- W1978496745 modified "2023-09-30" @default.
- W1978496745 title "Internal and 3′ RNA Initiation by Qβ Replicase Directed by CCA Boxes" @default.
- W1978496745 cites W112836397 @default.
- W1978496745 cites W1541892611 @default.
- W1978496745 cites W1932632320 @default.
- W1978496745 cites W1966297612 @default.
- W1978496745 cites W1973871691 @default.
- W1978496745 cites W1974309820 @default.
- W1978496745 cites W1977863283 @default.
- W1978496745 cites W1985832902 @default.
- W1978496745 cites W1993837131 @default.
- W1978496745 cites W2015334704 @default.
- W1978496745 cites W2037909536 @default.
- W1978496745 cites W2044994253 @default.
- W1978496745 cites W2061432433 @default.
- W1978496745 cites W2073641163 @default.
- W1978496745 cites W2081407528 @default.
- W1978496745 cites W2085272777 @default.
- W1978496745 cites W2106011441 @default.
- W1978496745 cites W2115975403 @default.
- W1978496745 cites W2116527854 @default.
- W1978496745 cites W2136285267 @default.
- W1978496745 cites W2144700871 @default.
- W1978496745 cites W2145649504 @default.
- W1978496745 cites W2169484417 @default.
- W1978496745 cites W2007131946 @default.
- W1978496745 doi "https://doi.org/10.1006/viro.2000.0334" @default.
- W1978496745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10860889" @default.
- W1978496745 hasPublicationYear "2000" @default.
- W1978496745 type Work @default.
- W1978496745 sameAs 1978496745 @default.
- W1978496745 citedByCount "13" @default.
- W1978496745 countsByYear W19784967452013 @default.
- W1978496745 crossrefType "journal-article" @default.
- W1978496745 hasAuthorship W1978496745A5010610734 @default.
- W1978496745 hasAuthorship W1978496745A5046937914 @default.
- W1978496745 hasBestOaLocation W19784967451 @default.
- W1978496745 hasConcept C100299639 @default.
- W1978496745 hasConcept C104317684 @default.
- W1978496745 hasConcept C138885662 @default.
- W1978496745 hasConcept C153911025 @default.
- W1978496745 hasConcept C179926584 @default.
- W1978496745 hasConcept C41258723 @default.
- W1978496745 hasConcept C41895202 @default.
- W1978496745 hasConcept C54355233 @default.
- W1978496745 hasConcept C67705224 @default.
- W1978496745 hasConcept C86803240 @default.
- W1978496745 hasConceptScore W1978496745C100299639 @default.
- W1978496745 hasConceptScore W1978496745C104317684 @default.
- W1978496745 hasConceptScore W1978496745C138885662 @default.
- W1978496745 hasConceptScore W1978496745C153911025 @default.
- W1978496745 hasConceptScore W1978496745C179926584 @default.
- W1978496745 hasConceptScore W1978496745C41258723 @default.
- W1978496745 hasConceptScore W1978496745C41895202 @default.
- W1978496745 hasConceptScore W1978496745C54355233 @default.
- W1978496745 hasConceptScore W1978496745C67705224 @default.
- W1978496745 hasConceptScore W1978496745C86803240 @default.
- W1978496745 hasIssue "2" @default.
- W1978496745 hasLocation W19784967451 @default.
- W1978496745 hasLocation W19784967452 @default.
- W1978496745 hasOpenAccess W1978496745 @default.
- W1978496745 hasPrimaryLocation W19784967451 @default.
- W1978496745 hasRelatedWork W1485710531 @default.
- W1978496745 hasRelatedWork W1549780051 @default.
- W1978496745 hasRelatedWork W2009968618 @default.
- W1978496745 hasRelatedWork W2079028796 @default.
- W1978496745 hasRelatedWork W2080810206 @default.
- W1978496745 hasRelatedWork W2096619494 @default.
- W1978496745 hasRelatedWork W2099735766 @default.
- W1978496745 hasRelatedWork W2123297336 @default.
- W1978496745 hasRelatedWork W2136192876 @default.
- W1978496745 hasRelatedWork W4236292213 @default.
- W1978496745 hasVolume "271" @default.
- W1978496745 isParatext "false" @default.
- W1978496745 isRetracted "false" @default.
- W1978496745 magId "1978496745" @default.
- W1978496745 workType "article" @default.