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- W1978497845 abstract "Tyrosine hydroxylase (TH) is the rate-limiting enzyme for catecholamine biosynthesis and a candidate gene for manic-depressive illness. The TH locus was typed for a BglII RFLP using a cDNA clone Ty7 in four large kindreds. Pairwise analyses and multipoint analyses were carried out to map the TH locus more precisely in the region of the linked markers: D11S12, INS, and HRAS1 on 11p. Results confirm the close linkage between TH with these previously mapped markers and support a most likely ordering which places TH on the side of INS where the centromere lies." @default.
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- W1978497845 date "1988-05-01" @default.
- W1978497845 modified "2023-09-26" @default.
- W1978497845 title "Tyrosine hydroxylase maps to the short arm of chromosome 11 proximal to the insulin and HRAS1 loci" @default.
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- W1978497845 doi "https://doi.org/10.1016/0888-7543(88)90016-x" @default.
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