FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978523917> ?p ?o ?g. }

• W1978523917 abstract "An attempt has been made to define the extent to which metabolic flux in central plant metabolism is reflected by changes in the transcriptome and metabolome, based on an analysis of in vitro cultured immature embryos of two oilseed rape (Brassica napus) accessions which contrast for seed lipid accumulation. Metabolic flux analysis was used to constrain a flux balance metabolic model which included 671 biochemical and transport reactions within the central metabolism. This highly confident flux information was eventually used for comparative analysis of flux versus transcript (metabolite). Metabolite profiling succeeded in identifying 79 intermediates within the central metabolism, some of which differed quantitatively between the two accessions and displayed a significant shift corresponding to flux. An RNA-Seq based transcriptome analysis revealed a large number of genes which were differentially transcribed in the two accessions, including some enzymes/proteins active in major metabolic pathways. With a few exceptions, differential activity in the major pathways (glycolysis, TCA cycle, amino acid and fatty acid synthesis) was not reflected in contrasting abundances of the relevant transcripts. The conclusion was that transcript abundance on its own cannot be used to infer metabolic activity/fluxes in central plant metabolism. This limitation needs to be borne in mind in evaluating transcriptome data and designing metabolic engineering experiments." @default.
• W1978523917 created "2016-06-24" @default.
• W1978523917 creator A5010301856 @default.
• W1978523917 creator A5018101706 @default.
• W1978523917 creator A5018145007 @default.
• W1978523917 creator A5020613277 @default.
• W1978523917 creator A5020745906 @default.
• W1978523917 creator A5037156038 @default.
• W1978523917 creator A5040908598 @default.
• W1978523917 creator A5046599851 @default.
• W1978523917 creator A5056871325 @default.
• W1978523917 creator A5064930656 @default.
• W1978523917 creator A5067834520 @default.
• W1978523917 creator A5071274755 @default.
• W1978523917 creator A5075360838 @default.
• W1978523917 creator A5078974058 @default.
• W1978523917 date "2014-11-28" @default.
• W1978523917 modified "2023-10-15" @default.
• W1978523917 title "Transcript abundance on its own cannot be used to infer fluxes in central metabolism" @default.
• W1978523917 cites W1581046505 @default.
• W1978523917 cites W1963489914 @default.
• W1978523917 cites W1978422034 @default.
• W1978523917 cites W1986662234 @default.
• W1978523917 cites W1999574084 @default.
• W1978523917 cites W2001084806 @default.
• W1978523917 cites W2006559324 @default.
• W1978523917 cites W2008115217 @default.
• W1978523917 cites W2009983406 @default.
• W1978523917 cites W2013142599 @default.
• W1978523917 cites W2014662834 @default.
• W1978523917 cites W2021513917 @default.
• W1978523917 cites W2032118099 @default.
• W1978523917 cites W2039315563 @default.
• W1978523917 cites W2040334106 @default.
• W1978523917 cites W2042355755 @default.
• W1978523917 cites W2058713700 @default.
• W1978523917 cites W2063947061 @default.
• W1978523917 cites W2068146784 @default.
• W1978523917 cites W2076716065 @default.
• W1978523917 cites W2081052511 @default.
• W1978523917 cites W2088933296 @default.
• W1978523917 cites W2089661821 @default.
• W1978523917 cites W2090046034 @default.
• W1978523917 cites W2097065948 @default.
• W1978523917 cites W2098489069 @default.
• W1978523917 cites W2098832713 @default.
• W1978523917 cites W2099363748 @default.
• W1978523917 cites W2103135236 @default.
• W1978523917 cites W2107277218 @default.
• W1978523917 cites W2107932973 @default.
• W1978523917 cites W2108357601 @default.
• W1978523917 cites W2111100441 @default.
• W1978523917 cites W2111653343 @default.
• W1978523917 cites W2117665293 @default.
• W1978523917 cites W2118348421 @default.
• W1978523917 cites W2119859261 @default.
• W1978523917 cites W2120024428 @default.
• W1978523917 cites W2126419817 @default.
• W1978523917 cites W2127627501 @default.
• W1978523917 cites W2129926698 @default.
• W1978523917 cites W2134245322 @default.
• W1978523917 cites W2137723667 @default.
• W1978523917 cites W2142270568 @default.
• W1978523917 cites W2152287977 @default.
• W1978523917 cites W2154754929 @default.
• W1978523917 cites W2157232904 @default.
• W1978523917 cites W2160761647 @default.
• W1978523917 cites W2169674481 @default.
• W1978523917 cites W2192080449 @default.
• W1978523917 cites W2398299089 @default.
• W1978523917 doi "https://doi.org/10.3389/fpls.2014.00668" @default.
• W1978523917 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4246676" @default.
• W1978523917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25506350" @default.
• W1978523917 hasPublicationYear "2014" @default.
• W1978523917 type Work @default.
• W1978523917 sameAs 1978523917 @default.
• W1978523917 citedByCount "47" @default.
• W1978523917 countsByYear W19785239172014 @default.
• W1978523917 countsByYear W19785239172015 @default.
• W1978523917 countsByYear W19785239172016 @default.
• W1978523917 countsByYear W19785239172017 @default.
• W1978523917 countsByYear W19785239172018 @default.
• W1978523917 countsByYear W19785239172019 @default.
• W1978523917 countsByYear W19785239172020 @default.
• W1978523917 countsByYear W19785239172021 @default.
• W1978523917 countsByYear W19785239172022 @default.
• W1978523917 countsByYear W19785239172023 @default.
• W1978523917 crossrefType "journal-article" @default.
• W1978523917 hasAuthorship W1978523917A5010301856 @default.
• W1978523917 hasAuthorship W1978523917A5018101706 @default.
• W1978523917 hasAuthorship W1978523917A5018145007 @default.
• W1978523917 hasAuthorship W1978523917A5020613277 @default.
• W1978523917 hasAuthorship W1978523917A5020745906 @default.
• W1978523917 hasAuthorship W1978523917A5037156038 @default.
• W1978523917 hasAuthorship W1978523917A5040908598 @default.
• W1978523917 hasAuthorship W1978523917A5046599851 @default.
• W1978523917 hasAuthorship W1978523917A5056871325 @default.
• W1978523917 hasAuthorship W1978523917A5064930656 @default.
• W1978523917 hasAuthorship W1978523917A5067834520 @default.
• W1978523917 hasAuthorship W1978523917A5071274755 @default.

• next