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- W1978542935 abstract "Structural and mechanistic information, sequence comparisons, and site-directed mutagenesis data continue to provide a basis for the rational design of new protein functions and the alteration of existing functions. Random mutagenesis and ‘directed evolution’ approaches, however, are making significant headway in solving protein engineering problems, proving highly practical for tuning properties such as enzyme substrate specificity." @default.
- W1978542935 created "2016-06-24" @default.
- W1978542935 creator A5067960799 @default.
- W1978542935 date "1996-08-01" @default.
- W1978542935 modified "2023-09-28" @default.
- W1978542935 title "Engineering new functions and altering existing functions" @default.
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- W1978542935 doi "https://doi.org/10.1016/s0959-440x(96)80117-5" @default.
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