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- W1978546972 abstract "An analysis was made of the ability of bone marrow cells derived from young (6 months) or old (28 months) murine (A X C57BL/6) donors to differentiate to B and T lymphocytes following serial bone marrow cell transplantations into groups of young syngeneic lethally irradiated recipients. Both number and mitogenic responsiveness of splenic B and T lymphocytes were recorded for recipients of young or old bone marrow cells 9 months following each serial transplant. The data suggests that lymphopoietic stem cells senescence in a manner analogous to that predicted by the clonal succession model of ageing." @default.
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- W1978546972 date "1985-11-01" @default.
- W1978546972 modified "2023-10-14" @default.
- W1978546972 title "The decline in murine splenic PHA and LPS responsiveness following serial transplantation of young and old bone marrow cells" @default.
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- W1978546972 doi "https://doi.org/10.1016/0047-6374(85)90083-1" @default.
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