FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978551878> ?p ?o ?g. }

• W1978551878 endingPage "1648" @default.
• W1978551878 startingPage "1643" @default.
• W1978551878 abstract "Cryptosporidium is a zoonotic protozoan that is most often diagnosed in association with diarrhea in 1- to 3-wk-old dairy calves. There are neither consistently effective nor approved antimicrobial drugs for treatment in animals. The objective of this study was to test nitazoxanide (NTZ) as a treatment for cryptosporidiosis in experimentally infected dairy calves. A randomized, controlled, and blinded trial was performed using Holstein bull calves obtained from a large commercial dairy. All births were attended by study personnel and calves were fed 4 L of heat-treated colostrum within 1 h of birth. Calves were randomly assigned to treatment or placebo group and maintained for a 32-feeding (16 d) study period. Twenty-three calves were enrolled with 3 lost to follow up. Thirteen calves were assigned to the treatment group and 7 calves to the placebo group. All calves were inoculated with 1 × 106 viable Cryptosporidium parvum oocysts at feeding 3. Treatment was a commercially available NTZ product and the placebo was the carrier of the same product. Nitazoxanide was administered at 1.5 g twice per day for 5 d. Nitazoxanide or placebo treatment began after feeding 10 and when the fecal score was greater than 1 out of 3. Outcome measurements included twice-daily fecal and health scores and a once-daily oocyst count by an immunofluorescent antibody assay. Data were analyzed by nonparametric and time-to-event methods. Measures of passive transfer of antibodies, initial body weight, and onset of oocyst shedding were not different between treatment and control calves. Eighty-five percent of the NTZ-treated calves stopped shedding oocysts by the end of the observation period whereas only 15% of the placebo group stopped shedding. The median number of feedings with a fecal score equal to 3 was 2 in the NTZ group while it was 6 in the placebo group. Calves receiving NTZ were 0.13 times as likely to have severe and sustained diarrhea than control calves (95% confidence interval, 0.02–0.98). Treating calves with NTZ reduced the duration of oocyst shedding and improved fecal consistency." @default.
• W1978551878 created "2016-06-24" @default.
• W1978551878 creator A5032778545 @default.
• W1978551878 creator A5034714249 @default.
• W1978551878 creator A5044710952 @default.
• W1978551878 creator A5065989470 @default.
• W1978551878 creator A5079317666 @default.
• W1978551878 creator A5088314579 @default.
• W1978551878 creator A5091128797 @default.
• W1978551878 date "2009-04-01" @default.
• W1978551878 modified "2023-09-27" @default.
• W1978551878 title "Effect of nitazoxanide on cryptosporidiosis in experimentally infected neonatal dairy calves" @default.
• W1978551878 cites W125455819 @default.
• W1978551878 cites W1893759965 @default.
• W1978551878 cites W2003365247 @default.
• W1978551878 cites W2021962539 @default.
• W1978551878 cites W2032939013 @default.
• W1978551878 cites W2045531461 @default.
• W1978551878 cites W2057609361 @default.
• W1978551878 cites W2059880516 @default.
• W1978551878 cites W2070575702 @default.
• W1978551878 cites W2074809486 @default.
• W1978551878 cites W2087203497 @default.
• W1978551878 cites W2094534595 @default.
• W1978551878 cites W2111148981 @default.
• W1978551878 cites W2122441393 @default.
• W1978551878 cites W2137850976 @default.
• W1978551878 cites W2145879140 @default.
• W1978551878 cites W2146853955 @default.
• W1978551878 cites W2160127483 @default.
• W1978551878 cites W2161745096 @default.
• W1978551878 cites W2315498992 @default.
• W1978551878 cites W4293241248 @default.
• W1978551878 doi "https://doi.org/10.3168/jds.2008-1474" @default.
• W1978551878 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19307646" @default.
• W1978551878 hasPublicationYear "2009" @default.
• W1978551878 type Work @default.
• W1978551878 sameAs 1978551878 @default.
• W1978551878 citedByCount "44" @default.
• W1978551878 countsByYear W19785518782012 @default.
• W1978551878 countsByYear W19785518782013 @default.
• W1978551878 countsByYear W19785518782014 @default.
• W1978551878 countsByYear W19785518782015 @default.
• W1978551878 countsByYear W19785518782016 @default.
• W1978551878 countsByYear W19785518782017 @default.
• W1978551878 countsByYear W19785518782018 @default.
• W1978551878 countsByYear W19785518782019 @default.
• W1978551878 countsByYear W19785518782020 @default.
• W1978551878 countsByYear W19785518782021 @default.
• W1978551878 countsByYear W19785518782022 @default.
• W1978551878 countsByYear W19785518782023 @default.
• W1978551878 crossrefType "journal-article" @default.
• W1978551878 hasAuthorship W1978551878A5032778545 @default.
• W1978551878 hasAuthorship W1978551878A5034714249 @default.
• W1978551878 hasAuthorship W1978551878A5044710952 @default.
• W1978551878 hasAuthorship W1978551878A5065989470 @default.
• W1978551878 hasAuthorship W1978551878A5079317666 @default.
• W1978551878 hasAuthorship W1978551878A5088314579 @default.
• W1978551878 hasAuthorship W1978551878A5091128797 @default.
• W1978551878 hasBestOaLocation W19785518781 @default.
• W1978551878 hasConcept C126322002 @default.
• W1978551878 hasConcept C140793950 @default.
• W1978551878 hasConcept C142724271 @default.
• W1978551878 hasConcept C159654299 @default.
• W1978551878 hasConcept C203014093 @default.
• W1978551878 hasConcept C204787440 @default.
• W1978551878 hasConcept C27081682 @default.
• W1978551878 hasConcept C2777276848 @default.
• W1978551878 hasConcept C2778877831 @default.
• W1978551878 hasConcept C2779073587 @default.
• W1978551878 hasConcept C2779802037 @default.
• W1978551878 hasConcept C42972112 @default.
• W1978551878 hasConcept C61716771 @default.
• W1978551878 hasConcept C71924100 @default.
• W1978551878 hasConcept C86803240 @default.
• W1978551878 hasConcept C89423630 @default.
• W1978551878 hasConceptScore W1978551878C126322002 @default.
• W1978551878 hasConceptScore W1978551878C140793950 @default.
• W1978551878 hasConceptScore W1978551878C142724271 @default.
• W1978551878 hasConceptScore W1978551878C159654299 @default.
• W1978551878 hasConceptScore W1978551878C203014093 @default.
• W1978551878 hasConceptScore W1978551878C204787440 @default.
• W1978551878 hasConceptScore W1978551878C27081682 @default.
• W1978551878 hasConceptScore W1978551878C2777276848 @default.
• W1978551878 hasConceptScore W1978551878C2778877831 @default.
• W1978551878 hasConceptScore W1978551878C2779073587 @default.
• W1978551878 hasConceptScore W1978551878C2779802037 @default.
• W1978551878 hasConceptScore W1978551878C42972112 @default.
• W1978551878 hasConceptScore W1978551878C61716771 @default.
• W1978551878 hasConceptScore W1978551878C71924100 @default.
• W1978551878 hasConceptScore W1978551878C86803240 @default.
• W1978551878 hasConceptScore W1978551878C89423630 @default.
• W1978551878 hasIssue "4" @default.
• W1978551878 hasLocation W19785518781 @default.
• W1978551878 hasLocation W19785518782 @default.
• W1978551878 hasOpenAccess W1978551878 @default.
• W1978551878 hasPrimaryLocation W19785518781 @default.
• W1978551878 hasRelatedWork W180298543 @default.

• next