FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978562772> ?p ?o ?g. }

• W1978562772 endingPage "434" @default.
• W1978562772 startingPage "427" @default.
• W1978562772 abstract "Hexahydro-1,3,5-trinitro-1,3,5-triazine, a polynitramine compound, commonly known as RDX, has been used as an explosive in military munitions formulations since World War II. There is considerable data available regarding the toxicity and carcinogenicity of RDX. It has been classified as a possible carcinogen (U.S. Environmental Protection Agency, Integrated Risk Information System, 2005, www.epa.gov/IRIS/subst/0313.htm). In order to better understand its gentoxic potential, the authors conducted the in vitro mouse lymphoma forward mutation and the in vivo mouse bone marrow micronucleus assays. Pure RDX (99.99%) at concentrations ranging from 3.93 to 500 microg/ml showed no cytotoxicity and no mutagenicity in forward mutations at the thymidine kinase (TK) locus in L5178Y mouse lymphoma cells, with and without metabolic activation. This finding was also confirmed by repeat assays under identical conditions. In addition, RDX did not induce micronuclei in mouse bone marrow cells when tested to the maximum tolerated dose of 250 mg/kg in male mice. These results show that RDX was not mutagenic in these in vitro and in vivo mammalian systems." @default.
• W1978562772 created "2016-06-24" @default.
• W1978562772 creator A5026327532 @default.
• W1978562772 creator A5042511305 @default.
• W1978562772 creator A5075084768 @default.
• W1978562772 creator A5083017227 @default.
• W1978562772 creator A5054884395 @default.
• W1978562772 date "2005-11-01" @default.
• W1978562772 modified "2023-10-16" @default.
• W1978562772 title "Genotoxicity Assessment of Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX)" @default.
• W1978562772 cites W1981808928 @default.
• W1978562772 cites W1994902349 @default.
• W1978562772 cites W2008838636 @default.
• W1978562772 cites W2013076264 @default.
• W1978562772 cites W2022042640 @default.
• W1978562772 cites W2027497795 @default.
• W1978562772 cites W2032934991 @default.
• W1978562772 cites W2035263815 @default.
• W1978562772 cites W2046024062 @default.
• W1978562772 cites W2073078196 @default.
• W1978562772 cites W2098134744 @default.
• W1978562772 cites W2105806537 @default.
• W1978562772 cites W2254096176 @default.
• W1978562772 cites W2503212472 @default.
• W1978562772 doi "https://doi.org/10.1080/10915810500366922" @default.
• W1978562772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16393935" @default.
• W1978562772 hasPublicationYear "2005" @default.
• W1978562772 type Work @default.
• W1978562772 sameAs 1978562772 @default.
• W1978562772 citedByCount "11" @default.
• W1978562772 countsByYear W19785627722012 @default.
• W1978562772 countsByYear W19785627722013 @default.
• W1978562772 countsByYear W19785627722021 @default.
• W1978562772 crossrefType "journal-article" @default.
• W1978562772 hasAuthorship W1978562772A5026327532 @default.
• W1978562772 hasAuthorship W1978562772A5042511305 @default.
• W1978562772 hasAuthorship W1978562772A5054884395 @default.
• W1978562772 hasAuthorship W1978562772A5075084768 @default.
• W1978562772 hasAuthorship W1978562772A5083017227 @default.
• W1978562772 hasBestOaLocation W19785627721 @default.
• W1978562772 hasConcept C104317684 @default.
• W1978562772 hasConcept C109316439 @default.
• W1978562772 hasConcept C114246631 @default.
• W1978562772 hasConcept C150194340 @default.
• W1978562772 hasConcept C178790620 @default.
• W1978562772 hasConcept C185592680 @default.
• W1978562772 hasConcept C202751555 @default.
• W1978562772 hasConcept C203014093 @default.
• W1978562772 hasConcept C207001950 @default.
• W1978562772 hasConcept C2776639595 @default.
• W1978562772 hasConcept C2778959862 @default.
• W1978562772 hasConcept C2780007613 @default.
• W1978562772 hasConcept C29730261 @default.
• W1978562772 hasConcept C33070731 @default.
• W1978562772 hasConcept C45080847 @default.
• W1978562772 hasConcept C54355233 @default.
• W1978562772 hasConcept C55493867 @default.
• W1978562772 hasConcept C86803240 @default.
• W1978562772 hasConcept C93231420 @default.
• W1978562772 hasConcept C98274493 @default.
• W1978562772 hasConceptScore W1978562772C104317684 @default.
• W1978562772 hasConceptScore W1978562772C109316439 @default.
• W1978562772 hasConceptScore W1978562772C114246631 @default.
• W1978562772 hasConceptScore W1978562772C150194340 @default.
• W1978562772 hasConceptScore W1978562772C178790620 @default.
• W1978562772 hasConceptScore W1978562772C185592680 @default.
• W1978562772 hasConceptScore W1978562772C202751555 @default.
• W1978562772 hasConceptScore W1978562772C203014093 @default.
• W1978562772 hasConceptScore W1978562772C207001950 @default.
• W1978562772 hasConceptScore W1978562772C2776639595 @default.
• W1978562772 hasConceptScore W1978562772C2778959862 @default.
• W1978562772 hasConceptScore W1978562772C2780007613 @default.
• W1978562772 hasConceptScore W1978562772C29730261 @default.
• W1978562772 hasConceptScore W1978562772C33070731 @default.
• W1978562772 hasConceptScore W1978562772C45080847 @default.
• W1978562772 hasConceptScore W1978562772C54355233 @default.
• W1978562772 hasConceptScore W1978562772C55493867 @default.
• W1978562772 hasConceptScore W1978562772C86803240 @default.
• W1978562772 hasConceptScore W1978562772C93231420 @default.
• W1978562772 hasConceptScore W1978562772C98274493 @default.
• W1978562772 hasIssue "6" @default.
• W1978562772 hasLocation W19785627721 @default.
• W1978562772 hasLocation W19785627722 @default.
• W1978562772 hasOpenAccess W1978562772 @default.
• W1978562772 hasPrimaryLocation W19785627721 @default.
• W1978562772 hasRelatedWork W1957565121 @default.
• W1978562772 hasRelatedWork W2022422131 @default.
• W1978562772 hasRelatedWork W2028804678 @default.
• W1978562772 hasRelatedWork W2047762210 @default.
• W1978562772 hasRelatedWork W2068648707 @default.
• W1978562772 hasRelatedWork W2082861567 @default.
• W1978562772 hasRelatedWork W2091355127 @default.
• W1978562772 hasRelatedWork W2156827867 @default.
• W1978562772 hasRelatedWork W2734568297 @default.
• W1978562772 hasRelatedWork W3208312538 @default.
• W1978562772 hasVolume "24" @default.
• W1978562772 isParatext "false" @default.
• W1978562772 isRetracted "false" @default.

• next