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• W1978577647 abstract "In the young rat, the concentration of thyroxine in the plasma progressively augments from birth to the third postnatal week. The plasma thyroxine turnover is also significantly higher during this period than at 30 days or in the adult. In the propylthiouracil-treated animal, the minimal daily dose of exogenous thyroxine able to correct the structural maturation of the cerebellar Purkinje cells and of their afferents also returns the electrophysiological maturation of the Purkinje cells to normal. Furthermore, this minimal daily dose prevents the enlargement of the thyroid gland, and it corresponds to the amount of hormone normally produced per day by the thyroid. The sensitivity of the cerebellar structures appears earlier and consequently is higher than that of the structures giving birth to the postnatal ossification centers." @default.
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• W1978577647 date "1974-06-01" @default.
• W1978577647 modified "2023-10-03" @default.
• W1978577647 title "Thyroid physiology during the postnatal period in the rat: A study of the development of thyroid function and of the morphogenetic effects of thyroxine with special reference to cerebellar maturation" @default.
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• W1978577647 doi "https://doi.org/10.1016/0016-6480(74)90127-0" @default.
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