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• W1978590919 abstract "This prospective study designed to assess the safety and short and intermediate term efficacy of drug-eluting balloon (DEB) in the treatment of de-novo, in-stent restenotis and bifurcation coronary artery disease (CAD) in Saudi Arabic Population. Total of 64 patients so far enrolled in a prospective registry using a Be Brown Paclitaxel-coated balloon (DEB) at our hospital, 61 patients were studied for short and intermediate term outcomes (6 to 12 months). All patients with symptomatic CAD including 21 patients 33% of de-novo lesions, 25 patients 39% of in-stent restenosis (ISR) and 17 patients 28% of bifurcation lesions requiring percutaneous intervention (PCI) with a DEB were included. Clinical follow-up was conducted at 6 and 12 months. Coronary angiography (CAG) or SPECT Scan were done in 71% of patients during this period. Primary outcome was a composite of target vessel revascularization and mortality. Procedural success was achieved in 96% of the patients. Two patients were failed due to failed DEB to cross heavily calcified vessel. Mean age was 60.8 ± 30 years. 47 patients 77% presented with Stable angina and 9 patients 15% with acute coronary syndrome (ACS). Twenty five patients 41% had triple vessel CAD. Sixty percent were classified as having ACC/AHA B-2 or C type coronary arteries including 26% patients with bifurcation lesions. Lesions stenting post DEB required in 8 patients 13% due to either dissection (4 patients) or inadequate result (4 patients). Mean DEB diameter was 2.2 ± 0.5 mm (2 to 3.5 mm)and mean length was 19.3 ± 8 mm (10 to 30 mm). Immediate result mean diameter stenosis was 80% ± 8 decrease to 5% ± 9 post DEB dilatation and the diameter stenosis reached 15% ± 20 with coronary angiography follow up at 6 to 12 months. A 7 patients 11% has restenosis (6 patients from ISR group and one patients from bifurcation lesions group) the 7 patients required revascularization (5 patients has PCI and 2 patients has CABG). A 37 patients 59% who were followed by either recath (17 patients) or SPECT Scan (20 patients) showed no evidence of restenosis. The remained 17 patients 30% were followed clinically and showed no Angina. One patient died from cancer one month after PCI. There was no cerebrovascular accident and no major bleeding. Be Brown Paclitaxel-coated balloon (DEB) can be used safely with good and successful intermediate result with target vessel restenosis of 7 patients 11.3% (5 patients has PCI and 2 patients has CABG) and non cardiac mortality of 1.6%." @default.
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• W1978590919 date "2013-04-01" @default.
• W1978590919 modified "2023-10-17" @default.
• W1978590919 title "Drug-eluting balloon for de-novo, ISR and bifurcation lesions cad:Short and intermediate results, prospective registry" @default.
• W1978590919 doi "https://doi.org/10.1016/j.jsha.2013.03.157" @default.
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