FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978614152> ?p ?o ?g. }

• W1978614152 endingPage "136" @default.
• W1978614152 startingPage "129" @default.
• W1978614152 abstract "Abstract Opioid analgesics are effective therapeutic agents for malignant and nonmalignant pain, but their use is often compromised by unwanted adverse effects on the central nervous system and gastrointestinal (GI) tract. These adverse effects include sedation, respiratory depression, nausea and vomiting, reduction in biliary and pancreatic secretions, decreased GI motility, increased GI transit time, and subsequent constipation. The goal of this study was to determine national estimates of laxative use, with and without concurrent opioids, in the long-term care (LTC) population and to determine factors associated with laxative underuse among elderly LTC residents receiving opioids. This cross-sectional study was conducted in LTC facilities in the United States. Medicare beneficiaries participating in the Medicare Current Beneficiary Survey (MCBS) aged ≥65 years residing at least 1 month in a nursing home or assisted living facility in 2001 were considered eligible. Monthly and annual measures of laxative and opioid use were developed to estimate prevalence of drug use in the LTC population. Multivariable logistic regression was used to determine factors associated with the use of laxatives. Among our sample of 867 MCBS beneficiaries (mean [SD]age, 85.0 [7.7] years), 281 (32%) received at least 1 opioid at some time during 2001. Of these 281 patients, 186 (66%) were administered at least 1 laxative at any time of the year. We found that the mean monthly prevalence of concurrent opioid and laxative use was 55% (476/867). There was a low prevalence of as-needed laxative and opioid use; 96% of resident-months were identified as scheduled bowel regimen administrations, and 89% of resident-months with opioid use had ≥3 opioid administrations. The results of the multivariable analysis showed that white, female, and currently married patients spend 227% (P < 0.007), 52% (p < 0.008), and 39% (P < 0.02), respectively, more months with at least 1 administration of a laxative and an opioid than their counterpart nonwhite, male, unmarried patients, Comorbidities were not associated with laxative prophylaxis. Although laxatives are widely recommended in patients taking opioids, only 66% of elderly LTC residents in this study received this standard of care." @default.
• W1978614152 created "2016-06-24" @default.
• W1978614152 creator A5021794865 @default.
• W1978614152 creator A5039663913 @default.
• W1978614152 creator A5046691229 @default.
• W1978614152 creator A5085920834 @default.
• W1978614152 date "2007-06-01" @default.
• W1978614152 modified "2023-10-01" @default.
• W1978614152 title "Prophylaxis for opioid-induced constipation in elderly long-term care residents: A cross-sectional study of medicare beneficiaries" @default.
• W1978614152 cites W106147234 @default.
• W1978614152 cites W1544241773 @default.
• W1978614152 cites W1596883269 @default.
• W1978614152 cites W1986027267 @default.
• W1978614152 cites W2000535019 @default.
• W1978614152 cites W2036895238 @default.
• W1978614152 cites W2037112556 @default.
• W1978614152 cites W2053718507 @default.
• W1978614152 cites W2089605769 @default.
• W1978614152 cites W2132469876 @default.
• W1978614152 cites W2143221646 @default.
• W1978614152 cites W2329526937 @default.
• W1978614152 doi "https://doi.org/10.1016/j.amjopharm.2007.06.003" @default.
• W1978614152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17719515" @default.
• W1978614152 hasPublicationYear "2007" @default.
• W1978614152 type Work @default.
• W1978614152 sameAs 1978614152 @default.
• W1978614152 citedByCount "19" @default.
• W1978614152 countsByYear W19786141522014 @default.
• W1978614152 countsByYear W19786141522015 @default.
• W1978614152 countsByYear W19786141522016 @default.
• W1978614152 countsByYear W19786141522018 @default.
• W1978614152 countsByYear W19786141522022 @default.
• W1978614152 crossrefType "journal-article" @default.
• W1978614152 hasAuthorship W1978614152A5021794865 @default.
• W1978614152 hasAuthorship W1978614152A5039663913 @default.
• W1978614152 hasAuthorship W1978614152A5046691229 @default.
• W1978614152 hasAuthorship W1978614152A5085920834 @default.
• W1978614152 hasConcept C126322002 @default.
• W1978614152 hasConcept C142052008 @default.
• W1978614152 hasConcept C142724271 @default.
• W1978614152 hasConcept C170493617 @default.
• W1978614152 hasConcept C194828623 @default.
• W1978614152 hasConcept C197934379 @default.
• W1978614152 hasConcept C2780580376 @default.
• W1978614152 hasConcept C2780661987 @default.
• W1978614152 hasConcept C2780852908 @default.
• W1978614152 hasConcept C2781063702 @default.
• W1978614152 hasConcept C2781112942 @default.
• W1978614152 hasConcept C2908647359 @default.
• W1978614152 hasConcept C71924100 @default.
• W1978614152 hasConcept C99454951 @default.
• W1978614152 hasConceptScore W1978614152C126322002 @default.
• W1978614152 hasConceptScore W1978614152C142052008 @default.
• W1978614152 hasConceptScore W1978614152C142724271 @default.
• W1978614152 hasConceptScore W1978614152C170493617 @default.
• W1978614152 hasConceptScore W1978614152C194828623 @default.
• W1978614152 hasConceptScore W1978614152C197934379 @default.
• W1978614152 hasConceptScore W1978614152C2780580376 @default.
• W1978614152 hasConceptScore W1978614152C2780661987 @default.
• W1978614152 hasConceptScore W1978614152C2780852908 @default.
• W1978614152 hasConceptScore W1978614152C2781063702 @default.
• W1978614152 hasConceptScore W1978614152C2781112942 @default.
• W1978614152 hasConceptScore W1978614152C2908647359 @default.
• W1978614152 hasConceptScore W1978614152C71924100 @default.
• W1978614152 hasConceptScore W1978614152C99454951 @default.
• W1978614152 hasIssue "2" @default.
• W1978614152 hasLocation W19786141521 @default.
• W1978614152 hasLocation W19786141522 @default.
• W1978614152 hasOpenAccess W1978614152 @default.
• W1978614152 hasPrimaryLocation W19786141521 @default.
• W1978614152 hasRelatedWork W130012275 @default.
• W1978614152 hasRelatedWork W2279527025 @default.
• W1978614152 hasRelatedWork W2321256353 @default.
• W1978614152 hasRelatedWork W2358248846 @default.
• W1978614152 hasRelatedWork W2410473272 @default.
• W1978614152 hasRelatedWork W2411848747 @default.
• W1978614152 hasRelatedWork W2414252117 @default.
• W1978614152 hasRelatedWork W243857094 @default.
• W1978614152 hasRelatedWork W3009301004 @default.
• W1978614152 hasRelatedWork W4286267926 @default.
• W1978614152 hasVolume "5" @default.
• W1978614152 isParatext "false" @default.
• W1978614152 isRetracted "false" @default.
• W1978614152 magId "1978614152" @default.
• W1978614152 workType "article" @default.