FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978628640> ?p ?o ?g. }

• W1978628640 endingPage "305" @default.
• W1978628640 startingPage "300" @default.
• W1978628640 abstract "The purpose of this study was to determine whether Toll-like receptor 5 (TLR5) expression was associated with disease progression in cervical neoplasia. TLR5 expression was evaluated by immunohistochemistry (IHC) in 55 formalin-fixed paraffin-embedded cervical tissues; 10 normal cervical specimens, 9 low-grade cervical intraepithelial neoplasias (CINs), 12 high-grade CINs, and 24 invasive squamous cell carcinomas (ISCCs). TLR5 expression was also evaluated at the RNA level, in fresh, frozen cervical carcinoma tissues by real-time quantitative RT-PCR. TLR5 expression, which was mainly observed as cytoplasmic staining, gradually increased in accordance with the histopathologic grade in the following order: low-grade CIN less than high-grade CIN less than ISCC ( P < 0.001). Immunohistochemical staining showed that TLR5 expression was undetectable (80%) or weak (20%) in normal cervical squamous epithelial tissues. However, moderate expression was detected in 33.3% of low-grade CIN (3/9), 41.7% of high-grade CIN (5/12), and 45.8% of ISCC (11/24). Strong expression was detected in as much as 33.3% of high-grade CIN (4/12) and 50% of ISCC (12/24). Contrary to IHC results, real-time quantitative RT-PCR revealed that TLR5 expression in tumors was not statistically different compared to normal cervical tissues ( P = 0.1452). The IHC result suggests that TLR5 may play a significant role in tumor progression of cervical neoplasia and may represent a useful marker for malignant transformation of cervical squamous cells." @default.
• W1978628640 created "2016-06-24" @default.
• W1978628640 creator A5010694999 @default.
• W1978628640 creator A5020848688 @default.
• W1978628640 creator A5039617113 @default.
• W1978628640 creator A5044962782 @default.
• W1978628640 creator A5061006522 @default.
• W1978628640 creator A5073802304 @default.
• W1978628640 creator A5077795933 @default.
• W1978628640 creator A5080577940 @default.
• W1978628640 date "2008-01-01" @default.
• W1978628640 modified "2023-10-17" @default.
• W1978628640 title "Increased expression of Toll-like receptor 5 during progression of cervical neoplasia" @default.
• W1978628640 cites W1483162601 @default.
• W1978628640 cites W1514540900 @default.
• W1978628640 cites W1519633296 @default.
• W1978628640 cites W1947610403 @default.
• W1978628640 cites W1974666828 @default.
• W1978628640 cites W1995744610 @default.
• W1978628640 cites W2004465286 @default.
• W1978628640 cites W2004791006 @default.
• W1978628640 cites W2007019498 @default.
• W1978628640 cites W2047376205 @default.
• W1978628640 cites W2054210108 @default.
• W1978628640 cites W2057068754 @default.
• W1978628640 cites W2066201797 @default.
• W1978628640 cites W2070149147 @default.
• W1978628640 cites W2076361525 @default.
• W1978628640 cites W2101363646 @default.
• W1978628640 cites W2124093732 @default.
• W1978628640 cites W2129319296 @default.
• W1978628640 cites W2140283236 @default.
• W1978628640 cites W2142241097 @default.
• W1978628640 cites W2142414417 @default.
• W1978628640 cites W2168522148 @default.
• W1978628640 cites W2501221340 @default.
• W1978628640 cites W4236842068 @default.
• W1978628640 doi "https://doi.org/10.1111/j.1525-1438.2007.01008.x" @default.
• W1978628640 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17587322" @default.
• W1978628640 hasPublicationYear "2008" @default.
• W1978628640 type Work @default.
• W1978628640 sameAs 1978628640 @default.
• W1978628640 citedByCount "71" @default.
• W1978628640 countsByYear W19786286402012 @default.
• W1978628640 countsByYear W19786286402013 @default.
• W1978628640 countsByYear W19786286402014 @default.
• W1978628640 countsByYear W19786286402015 @default.
• W1978628640 countsByYear W19786286402016 @default.
• W1978628640 countsByYear W19786286402017 @default.
• W1978628640 countsByYear W19786286402018 @default.
• W1978628640 countsByYear W19786286402019 @default.
• W1978628640 countsByYear W19786286402020 @default.
• W1978628640 countsByYear W19786286402021 @default.
• W1978628640 countsByYear W19786286402022 @default.
• W1978628640 crossrefType "journal-article" @default.
• W1978628640 hasAuthorship W1978628640A5010694999 @default.
• W1978628640 hasAuthorship W1978628640A5020848688 @default.
• W1978628640 hasAuthorship W1978628640A5039617113 @default.
• W1978628640 hasAuthorship W1978628640A5044962782 @default.
• W1978628640 hasAuthorship W1978628640A5061006522 @default.
• W1978628640 hasAuthorship W1978628640A5073802304 @default.
• W1978628640 hasAuthorship W1978628640A5077795933 @default.
• W1978628640 hasAuthorship W1978628640A5080577940 @default.
• W1978628640 hasConcept C121608353 @default.
• W1978628640 hasConcept C126322002 @default.
• W1978628640 hasConcept C142724271 @default.
• W1978628640 hasConcept C170493617 @default.
• W1978628640 hasConcept C204232928 @default.
• W1978628640 hasConcept C2776070231 @default.
• W1978628640 hasConcept C2777338127 @default.
• W1978628640 hasConcept C2777343196 @default.
• W1978628640 hasConcept C2778220009 @default.
• W1978628640 hasConcept C2781236682 @default.
• W1978628640 hasConcept C71924100 @default.
• W1978628640 hasConcept C74864618 @default.
• W1978628640 hasConceptScore W1978628640C121608353 @default.
• W1978628640 hasConceptScore W1978628640C126322002 @default.
• W1978628640 hasConceptScore W1978628640C142724271 @default.
• W1978628640 hasConceptScore W1978628640C170493617 @default.
• W1978628640 hasConceptScore W1978628640C204232928 @default.
• W1978628640 hasConceptScore W1978628640C2776070231 @default.
• W1978628640 hasConceptScore W1978628640C2777338127 @default.
• W1978628640 hasConceptScore W1978628640C2777343196 @default.
• W1978628640 hasConceptScore W1978628640C2778220009 @default.
• W1978628640 hasConceptScore W1978628640C2781236682 @default.
• W1978628640 hasConceptScore W1978628640C71924100 @default.
• W1978628640 hasConceptScore W1978628640C74864618 @default.
• W1978628640 hasIssue "2" @default.
• W1978628640 hasLocation W19786286401 @default.
• W1978628640 hasLocation W19786286402 @default.
• W1978628640 hasOpenAccess W1978628640 @default.
• W1978628640 hasPrimaryLocation W19786286401 @default.
• W1978628640 hasRelatedWork W1770445976 @default.
• W1978628640 hasRelatedWork W2066381235 @default.
• W1978628640 hasRelatedWork W2082508773 @default.
• W1978628640 hasRelatedWork W2216064173 @default.
• W1978628640 hasRelatedWork W2369276577 @default.
• W1978628640 hasRelatedWork W2378888248 @default.

• next