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- W1978648317 abstract "With appropriate variation of the pH, alkali halogenide concentration and cation and/or anion species in the mobile phase (mixtures of water and methanol), it was possible to resolve diphenhydramine, N-desmethyldiphenhydramine, N,N-didesmethyldiphenhydramine, benzhydrol, benzophenone and 2-methyldiphenylmethoxy acetic acid on a reversed-phase column. The retention volumes of the three amines decreased by increasing the following parameters: salt concentration, methanol concentration and cation and/or anion size. The retention volumes of the other compounds were not influenced. The good separation and the simplicity make this method attractive for use in metabolism studies." @default.
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- W1978648317 date "1980-01-01" @default.
- W1978648317 modified "2023-09-23" @default.
- W1978648317 title "High-Pressure Liquid Chromatographic Separation of Diphenhydramine and Some of its Metabolites: Effects of Eluent Salt Concentration on Chromatographic Characteristics" @default.
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- W1978648317 doi "https://doi.org/10.1080/01483918008064749" @default.
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