FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978651108> ?p ?o ?g. }

• W1978651108 abstract "Our findings suggest that contrary to the proposed role for the nm23 protein as a tumor metastasis suppressor, in pancreatic tumors, the nm23 protein does not play an important role as a suppressor against tumor metastasis.The nm23 gene product, nucleotide diphosphate kinase, is believed to suppress tumor metastasis. Although a number of studies on many kinds of tumors have examined the relationship between nm23 expression and metastatic potential, the antimetastatic activity of nm23 remains controversial. The expression of the nm23 protein has not been examined in pancreatic tumors, except for a few reports on pancreatic duct cell carcinomas.We have investigated nm23 expression in pancreatic duct cell carcinomas, islet cell tumors, and ampullary carcinomas by immunohistochemical methods.In 73 cases of pancreatic duct cell carcinomas, the nm23 expression was increased when compared with the adjacent normal pancreatic ducts; diffuse immunostaining was detected in 21 (29%) cases, focally positive immunostaining in 47 (64%) cases, and negative immunostaining in 5 cases (7%). All five negative samples were obtained from distant metastatic regions. However, there was no significant difference in the nm23 expression between primary tumors and regional lymph node metastases. Furthermore, there was no significant correlation between nm23 expression and the prognosis of the 55 resected cases. In the 15 cases of ampullary carcinomas, all 15 tumors were positive for nm23 protein (6 diffuse and 9 focal), and the staining intensity was stronger than in normal pancreatic ducts. There was no significant difference in the nm23 expression in the primary regions between patients with and without lymph node metastasis (2 diffuse and 5 focal out of 7 patients with lymph node metastasis, and 4 diffuse and 4 focal out of 8 patients without lymph node metastasis). All 12 islet cell tumors showed strong and diffuse staining for the nm23 protein." @default.
• W1978651108 created "2016-06-24" @default.
• W1978651108 creator A5010089206 @default.
• W1978651108 creator A5016131649 @default.
• W1978651108 creator A5028433853 @default.
• W1978651108 creator A5030317114 @default.
• W1978651108 creator A5030499608 @default.
• W1978651108 creator A5053191594 @default.
• W1978651108 creator A5062584308 @default.
• W1978651108 creator A5077611996 @default.
• W1978651108 creator A5079511379 @default.
• W1978651108 date "1997-08-01" @default.
• W1978651108 modified "2023-09-26" @default.
• W1978651108 title "Immunohistochemical expression of nm23 gene product, nucleotide diphosphate kinase, in pancreatic neoplasms" @default.
• W1978651108 cites W1491326718 @default.
• W1978651108 cites W1517774220 @default.
• W1978651108 cites W1606316894 @default.
• W1978651108 cites W1673730923 @default.
• W1978651108 cites W1987199756 @default.
• W1978651108 cites W1992094660 @default.
• W1978651108 cites W2002940582 @default.
• W1978651108 cites W2005384382 @default.
• W1978651108 cites W2007599495 @default.
• W1978651108 cites W2018875909 @default.
• W1978651108 cites W2032841524 @default.
• W1978651108 cites W2039294009 @default.
• W1978651108 cites W2050316512 @default.
• W1978651108 cites W2068777108 @default.
• W1978651108 cites W2071326475 @default.
• W1978651108 cites W2072653261 @default.
• W1978651108 cites W2074800174 @default.
• W1978651108 cites W2076615266 @default.
• W1978651108 cites W2088358109 @default.
• W1978651108 cites W2104955946 @default.
• W1978651108 cites W2113047286 @default.
• W1978651108 cites W2114191414 @default.
• W1978651108 cites W2318196328 @default.
• W1978651108 cites W2319537756 @default.
• W1978651108 cites W283904446 @default.
• W1978651108 doi "https://doi.org/10.1007/bf02803906" @default.
• W1978651108 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9387026" @default.
• W1978651108 hasPublicationYear "1997" @default.
• W1978651108 type Work @default.
• W1978651108 sameAs 1978651108 @default.
• W1978651108 citedByCount "9" @default.
• W1978651108 countsByYear W19786511082012 @default.
• W1978651108 countsByYear W19786511082016 @default.
• W1978651108 countsByYear W19786511082018 @default.
• W1978651108 countsByYear W19786511082020 @default.
• W1978651108 crossrefType "journal-article" @default.
• W1978651108 hasAuthorship W1978651108A5010089206 @default.
• W1978651108 hasAuthorship W1978651108A5016131649 @default.
• W1978651108 hasAuthorship W1978651108A5028433853 @default.
• W1978651108 hasAuthorship W1978651108A5030317114 @default.
• W1978651108 hasAuthorship W1978651108A5030499608 @default.
• W1978651108 hasAuthorship W1978651108A5053191594 @default.
• W1978651108 hasAuthorship W1978651108A5062584308 @default.
• W1978651108 hasAuthorship W1978651108A5077611996 @default.
• W1978651108 hasAuthorship W1978651108A5079511379 @default.
• W1978651108 hasConcept C104317684 @default.
• W1978651108 hasConcept C121608353 @default.
• W1978651108 hasConcept C126322002 @default.
• W1978651108 hasConcept C142724271 @default.
• W1978651108 hasConcept C150194340 @default.
• W1978651108 hasConcept C151903565 @default.
• W1978651108 hasConcept C184235292 @default.
• W1978651108 hasConcept C195286587 @default.
• W1978651108 hasConcept C204232928 @default.
• W1978651108 hasConcept C2776737053 @default.
• W1978651108 hasConcept C2777996000 @default.
• W1978651108 hasConcept C2778025950 @default.
• W1978651108 hasConcept C2778264664 @default.
• W1978651108 hasConcept C2778764654 @default.
• W1978651108 hasConcept C2779013556 @default.
• W1978651108 hasConcept C2779960720 @default.
• W1978651108 hasConcept C2780210213 @default.
• W1978651108 hasConcept C2780849966 @default.
• W1978651108 hasConcept C2909960190 @default.
• W1978651108 hasConcept C4224716 @default.
• W1978651108 hasConcept C502942594 @default.
• W1978651108 hasConcept C55493867 @default.
• W1978651108 hasConcept C555283112 @default.
• W1978651108 hasConcept C71924100 @default.
• W1978651108 hasConcept C86803240 @default.
• W1978651108 hasConcept C95444343 @default.
• W1978651108 hasConceptScore W1978651108C104317684 @default.
• W1978651108 hasConceptScore W1978651108C121608353 @default.
• W1978651108 hasConceptScore W1978651108C126322002 @default.
• W1978651108 hasConceptScore W1978651108C142724271 @default.
• W1978651108 hasConceptScore W1978651108C150194340 @default.
• W1978651108 hasConceptScore W1978651108C151903565 @default.
• W1978651108 hasConceptScore W1978651108C184235292 @default.
• W1978651108 hasConceptScore W1978651108C195286587 @default.
• W1978651108 hasConceptScore W1978651108C204232928 @default.
• W1978651108 hasConceptScore W1978651108C2776737053 @default.
• W1978651108 hasConceptScore W1978651108C2777996000 @default.
• W1978651108 hasConceptScore W1978651108C2778025950 @default.
• W1978651108 hasConceptScore W1978651108C2778264664 @default.
• W1978651108 hasConceptScore W1978651108C2778764654 @default.
• W1978651108 hasConceptScore W1978651108C2779013556 @default.

• next