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- W1978661786 abstract "Glycosylphosphatidylinositol (GPI) anchoring of proteins is a conserved post‐translational modification in eukaryotes. In mammalian cells, approximately 150 proteins on the plasma membrane are attached to the cell surface by GPI anchors, which confer specific properties on proteins, such as association with membrane microdomains. The structures of lipid and glycan moieties on GPI anchors are remodeled during biosynthesis and after attachment to proteins. The remodeling processes are critical for transport and microdomain‐association of GPI‐anchored proteins. Here, we describe the structural remodeling of GPI anchors and genes required for the processes in mammals, yeast, and trypanosomes." @default.
- W1978661786 created "2016-06-24" @default.
- W1978661786 creator A5072623856 @default.
- W1978661786 creator A5082485542 @default.
- W1978661786 date "2009-10-31" @default.
- W1978661786 modified "2023-10-18" @default.
- W1978661786 title "Structural remodeling of GPI anchors during biosynthesis and after attachment to proteins" @default.
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- W1978661786 doi "https://doi.org/10.1016/j.febslet.2009.10.079" @default.
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