Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978667603> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1978667603 endingPage "443" @default.
- W1978667603 startingPage "439" @default.
- W1978667603 abstract "The changes induced in the level and turnover rate (TRACh) of acetylcholine (ACh) in the hippocampus and in the in vitro release of [3H]ACh by intracerebroventricular injection of trifluoperazine (TFP) were studied. Rats were killed by microwave irradiation at various times after treatment with drug or vehicle and the levels of ACh were measured by gas chromatography. After the administration of 100 micrograms trifluoperazine, the content of ACh of the whole hippocampus increased from 24.0 +/- 2.9 to 35.2 +/- 4.2 nmols/g wet weight over a 60 min period, while the turnover rate was markedly decreased (from 0.86 to 0.53 nmols/min/g wet tissue weight). The potassium-evoked release of [3H]ACh from slices of hippocampus under in vitro conditions was decreased in a concentration-dependent manner by preincubation with 50 and 100 microM of trifluoperazine for 60 min. The results support the assumption that trifluoperazine can alter neurotransmission, possibly by inhibiting the calcium-binding protein calmodulin, and/or by interfering with cell metabolism." @default.
- W1978667603 created "2016-06-24" @default.
- W1978667603 creator A5009290484 @default.
- W1978667603 creator A5079984424 @default.
- W1978667603 date "1987-05-01" @default.
- W1978667603 modified "2023-09-23" @default.
- W1978667603 title "Effects of trifluoperazine on the cholinergic function of the hippocampus of the rat" @default.
- W1978667603 cites W1990195443 @default.
- W1978667603 cites W2009817661 @default.
- W1978667603 cites W2011737473 @default.
- W1978667603 cites W2014225888 @default.
- W1978667603 cites W2014371167 @default.
- W1978667603 cites W2024657845 @default.
- W1978667603 cites W2027942102 @default.
- W1978667603 cites W2036357911 @default.
- W1978667603 cites W2052497364 @default.
- W1978667603 cites W2058685669 @default.
- W1978667603 cites W2089987469 @default.
- W1978667603 cites W2107277845 @default.
- W1978667603 cites W2116269157 @default.
- W1978667603 doi "https://doi.org/10.1016/0028-3908(87)90024-4" @default.
- W1978667603 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3037415" @default.
- W1978667603 hasPublicationYear "1987" @default.
- W1978667603 type Work @default.
- W1978667603 sameAs 1978667603 @default.
- W1978667603 citedByCount "5" @default.
- W1978667603 crossrefType "journal-article" @default.
- W1978667603 hasAuthorship W1978667603A5009290484 @default.
- W1978667603 hasAuthorship W1978667603A5079984424 @default.
- W1978667603 hasConcept C126322002 @default.
- W1978667603 hasConcept C134018914 @default.
- W1978667603 hasConcept C185592680 @default.
- W1978667603 hasConcept C202751555 @default.
- W1978667603 hasConcept C22885893 @default.
- W1978667603 hasConcept C2775891158 @default.
- W1978667603 hasConcept C2775910092 @default.
- W1978667603 hasConcept C2776711897 @default.
- W1978667603 hasConcept C2781161787 @default.
- W1978667603 hasConcept C29688787 @default.
- W1978667603 hasConcept C519063684 @default.
- W1978667603 hasConcept C55493867 @default.
- W1978667603 hasConcept C71924100 @default.
- W1978667603 hasConcept C86803240 @default.
- W1978667603 hasConcept C98274493 @default.
- W1978667603 hasConceptScore W1978667603C126322002 @default.
- W1978667603 hasConceptScore W1978667603C134018914 @default.
- W1978667603 hasConceptScore W1978667603C185592680 @default.
- W1978667603 hasConceptScore W1978667603C202751555 @default.
- W1978667603 hasConceptScore W1978667603C22885893 @default.
- W1978667603 hasConceptScore W1978667603C2775891158 @default.
- W1978667603 hasConceptScore W1978667603C2775910092 @default.
- W1978667603 hasConceptScore W1978667603C2776711897 @default.
- W1978667603 hasConceptScore W1978667603C2781161787 @default.
- W1978667603 hasConceptScore W1978667603C29688787 @default.
- W1978667603 hasConceptScore W1978667603C519063684 @default.
- W1978667603 hasConceptScore W1978667603C55493867 @default.
- W1978667603 hasConceptScore W1978667603C71924100 @default.
- W1978667603 hasConceptScore W1978667603C86803240 @default.
- W1978667603 hasConceptScore W1978667603C98274493 @default.
- W1978667603 hasIssue "5" @default.
- W1978667603 hasLocation W19786676031 @default.
- W1978667603 hasLocation W19786676032 @default.
- W1978667603 hasOpenAccess W1978667603 @default.
- W1978667603 hasPrimaryLocation W19786676031 @default.
- W1978667603 hasRelatedWork W1949746652 @default.
- W1978667603 hasRelatedWork W1978667603 @default.
- W1978667603 hasRelatedWork W1993142192 @default.
- W1978667603 hasRelatedWork W1995226963 @default.
- W1978667603 hasRelatedWork W2000051396 @default.
- W1978667603 hasRelatedWork W2045313643 @default.
- W1978667603 hasRelatedWork W2086892519 @default.
- W1978667603 hasRelatedWork W2093198910 @default.
- W1978667603 hasRelatedWork W2411949184 @default.
- W1978667603 hasRelatedWork W2417276995 @default.
- W1978667603 hasVolume "26" @default.
- W1978667603 isParatext "false" @default.
- W1978667603 isRetracted "false" @default.
- W1978667603 magId "1978667603" @default.
- W1978667603 workType "article" @default.