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- W1978687037 abstract "In recent years, the study of the peroxisome proliferators activated receptor gamma (PPAR-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>γ</mml:mi></mml:math>) as a potential target for cancer prevention and therapy has gained a strong interest. However, the overall biological significance of PPAR-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>γ</mml:mi></mml:math>in cancer development and progression is still controversial. While many reports documented antiproliferative effects in human cancer cell and animal models, several studies demonstrating potential tumor promoting actions of PPAR-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>γ</mml:mi></mml:math>ligands raised considerable concerns about the role of PPAR-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>γ</mml:mi></mml:math>in human cancers. Controversy also exists about the role of PPAR-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>γ</mml:mi></mml:math>in human pancreatic cancers. The current review summarizes the data about PPAR-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>γ</mml:mi></mml:math>in pancreatic cancer and highlights the biologically relevant interactions between the cyclooxygenase and PPAR system." @default.
- W1978687037 created "2016-06-24" @default.
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- W1978687037 date "2008-01-01" @default.
- W1978687037 modified "2023-10-17" @default.
- W1978687037 title "The Role of PPAR-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>γ</mml:mi></mml:math>and Its Interaction with COX-2 in Pancreatic Cancer" @default.
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- W1978687037 doi "https://doi.org/10.1155/2008/326915" @default.
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