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- W1978705217 abstract "We inserted a fluorene-labeled deoxyuridine derivative, synthesized using Sonogashira coupling, efficiently into the loop region of a DNA hairpin using phosphoramidite chemistry. This molecular beacon, which features no additional fluorescence quencher, discriminates between perfect and one-base-mismatched base pairing by changes in its fluorescence intensity. The discrimination factor is 14.7 for the recognition of a single (A/C) base mismatch." @default.
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- W1978705217 date "2004-05-08" @default.
- W1978705217 modified "2023-09-24" @default.
- W1978705217 title "A Highly Discriminating Quencher-Free Molecular Beacon for Probing DNA" @default.
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- W1978705217 doi "https://doi.org/10.1021/ja049795q" @default.
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