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- W1978708458 abstract "Dr Chua and colleagues have demonstrated a remarkably rapid and severe ocular hypertensive response to corticosteroid applied to the eyelid of a child. Similarly, corticosteroid-induced glaucoma may result from preparations applied to the periocular skin in adults, and the effect is most likely due to local absorption into the eye rather than systemic absorption.1Cubey RB Glaucoma following the application of corticosteroid to the skin of the eyelids.Br J Dermaioi. 1976; 95: 207-208Crossref PubMed Scopus (80) Google Scholar Dr Chua's coinvestigators have previously published data indicating that such a dramatic steroid response in a child is not a rarity but actually may be more common and more rapid in onset than in an adult population.2Kwok AK Lam DS Ng JS Fan DS Chew SJ Tso MO Ocular-hypertensive response to topical steroids in children.Ophthalmology. 1997; 104: 2112-2116Abstract Full Text PDF PubMed Scopus (117) Google Scholar Another practical point that should be considered is the challenge of measuring IOP in a small child, a task that often requires sedation. Ocular symptoms, adequate slit-lamp and fundus examinations, and accurate visual field testing are also more difficult, or impossible, to obtain. The practitioner who does not have the expertise or equipment to evaluate for glaucoma in this age group should exercise extreme caution in prescribing ocular or periocular corticosteroid medications to a child. Accelerated Ocular Hypertensive Response After Application of Corticosteroid Ointment to a Child's EyelidMayo Clinic ProceedingsVol. 75Issue 5PreviewTo the Editor: We read with interest the article “Indiscriminate Use of Corticosteroid-Containing Eyedrops” by Drs Baratz and Hattenhauer.1 It is well established that prolonged use of topical ophthalmic corticosteroids can produce ocular hypertension and secondary open-angle glaucoma in susceptible individuals2 This is clearly illustrated in 2 of the 3 cases described by the authors. The response in children occurs more frequently, more severely, and more rapidly than that reported in adults.3,4 In one of our previous studies, it has been shown that 56% of children, all less than 10 years old, were high responders to topical 0.1% dexamethasone. Full-Text PDF" @default.
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- W1978708458 date "2000-05-01" @default.
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- W1978708458 title "Accelerated Ocular Hypertensive Response After Application of Corticosteroid Ointment to a Child's Eyelid: In Response" @default.
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