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- W1978729240 abstract "Abstract A study of protein and nucleic acid synthesis in Bacillus stearothermophilus was undertaken to find out how this organism survives at high temperatures and why it does not grow below 40°. Incorporation of amino acids into the organism was very low at temperatures up to 35–38°, then incorporation increases rapidly and reaches an optimum at 60°. There is a difference between B. stearothermophilus and Escherichia coli in the heats of activation of the overall process of incorporation which may explain why high temperature favours reactions in the thermophile. The main reason why B. stearothermophilus does not grow below 40° is the very low rate of entry of amino acids and of uracil into the cells. A suggestion that thermophiles can survive at high temperatures because they are able to repair any heat damage by rapid resynthesis of cell substances received support from the results of turnover studies. The thermophilic organism had a much higher rate of protein and nucleic acid turnover than the mesophile E. coli." @default.
- W1978729240 created "2016-06-24" @default.
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- W1978729240 date "1966-08-01" @default.
- W1978729240 modified "2023-09-25" @default.
- W1978729240 title "Amino acid uptake, protein and nucleic acid synthesis and turnover in Bacillus stearothermophilus" @default.
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- W1978729240 doi "https://doi.org/10.1016/0005-2787(66)90289-9" @default.
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