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- W1978764825 abstract "Abstract Newly-hatched chicks were given intracranial injections of lithium chloride either before or after being trained in a one-trial passive avoidance task. Twenty minutes after training, memory of the aversive experince was found to be unaffected regardless of the time injections had been given. Retrieval measured 24 hr later, however, was severely impaired in chicks that had been injected 4 min before training, less so in those injected 2 min before, and unaffected in chicks treated 10 sec after training. Thus, while LiCl does not interfere with mnemonic processes necessary for short-term retrieval, it does seem to act with a delayed effectiveness to disrupt an early stage in the development of long-term memory. Previous studies indicate that immediately upon training a metastable memory trace becomes activated which seems to function as behaviorally-retrievable memory for the next hour or so, and which, within the first 45 sec, induces the growth of a behaviorally latent precursor to long-term memory. The present effects of LiCl can be interpreted in these terms as having selectively disrupted formation of the latter precursor component." @default.
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- W1978764825 date "1973-08-01" @default.
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- W1978764825 title "Amnesic effects of lithium chloride in chicks" @default.
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- W1978764825 doi "https://doi.org/10.1016/0014-4886(73)90094-0" @default.
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