FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978797929> ?p ?o ?g. }

• W1978797929 endingPage "78" @default.
• W1978797929 startingPage "77" @default.
• W1978797929 abstract "The recent commentary on high rates of uncontrolled blood pressure (BP) and opportunities for health care providers in this Journal1 prompted an examination of treated but uncontrolled BP in relation to pulse wave velocity (PWV) in the Maine Syracuse Longitudinal Study (MSLS).2, 3 Cohen and Townsend noted that a Center for Disease Control analysis2 of National Health and Nutrition Examination Survey (NHANES) data (2003–2010) indicated that the presence of uncontrolled hypertension (≥140 mm Hg systolic and ≥90 mm Hg diastolic) in US adults was 53.5%.1 They further noted that approximately 45% of these individuals with uncontrolled hypertension were aware of their hypertension and were receiving treatment. In the community-based MSLS, beginning in 1975 and concluding in 2008, there were 7 serial waves of data collection.2, 3 After each wave of data collection, participants were made aware of prevalent and incident cardiovascular risk factors, including hypertension, and were referred to their physicians for treatment as usual. The 140/90 mm Hg criteria were the prevailing standards for BP control for waves 4 to 7 of the study. Failure to achieve control was observed for 40%, 41%, and 41% of the participants at waves 5, 6, and 7, respectively; polypharmacy was the predominant treatment mode. In the last wave of MSLS (wave 7) for a subset of individuals participating in PWV studies, 95% of individuals with hypertension were being treated.4 Of these, 46% had BP levels defined as uncontrolled using the 140/90 mm Hg criteria. Data for PWV (m/s) and BP (mm Hg) parameters for treated hypertensive MSLS participants at wave 7 are shown in Table 1 to illustrate differences relating to BP control status. PWV for persons with untreated normal BP was 8.9 m/s (not shown), which was significantly lower than values for either the controlled or uncontrolled BP groups (P<.001). The controlled and uncontrolled groups differed for sex but not for the 4 cardiovascular risk factors, age (years), diabetes mellitus, body mass index (>30 kg/m2), and total cholesterol (mg/dL) (Table 2). Prevalence of all multiple cardiovascular diseases combined was 14% of the total sample. Table 3 shows categorical regression coefficients (b) relating controlled vs uncontrolled BP groups to PWV. For all three covariate sets, significant associations remained with statistical adjustment for cardiovascular risk factors, although the magnitudes of the association were attenuated. Our data are not original with respect to evidence that hypertension is the predominant risk factor for higher levels of PWV and, by inference, arterial stiffness.5 Clearly a causal association between BP control and PWV cannot be inferred; however, we present these data to illustrate an opportunity for further research. PWV is the gold standard indirect measure of arterial stiffness and there is growing evidence that it is very important in the early detection of vascular diseases.5, 6 We especially need longitudinal studies and additional controlled clinical trials of medications that have been associated with reduction in PWV (eg, ACE inhibitors, calcium channel antagonists, and selective β-blocking agents).7 We also need trials with new candidate drugs that may facilitate the achievement of hypertension management goals without adding to what Cohen and Townsend1 describe as a “burdensome list of medications.”" @default.
• W1978797929 created "2016-06-24" @default.
• W1978797929 creator A5000090216 @default.
• W1978797929 creator A5014265448 @default.
• W1978797929 creator A5053484529 @default.
• W1978797929 creator A5088038013 @default.
• W1978797929 date "2013-11-04" @default.
• W1978797929 modified "2023-10-16" @default.
• W1978797929 title "High Rates of Uncontrolled Blood Pressure: Pulse Wave Velocity and Future Opportunities" @default.
• W1978797929 cites W2062435507 @default.
• W1978797929 cites W2108917507 @default.
• W1978797929 cites W2143286041 @default.
• W1978797929 cites W2169431351 @default.
• W1978797929 cites W23747989 @default.
• W1978797929 doi "https://doi.org/10.1111/jch.12226" @default.
• W1978797929 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24182327" @default.
• W1978797929 hasPublicationYear "2013" @default.
• W1978797929 type Work @default.
• W1978797929 sameAs 1978797929 @default.
• W1978797929 citedByCount "1" @default.
• W1978797929 countsByYear W19787979292017 @default.
• W1978797929 crossrefType "journal-article" @default.
• W1978797929 hasAuthorship W1978797929A5000090216 @default.
• W1978797929 hasAuthorship W1978797929A5014265448 @default.
• W1978797929 hasAuthorship W1978797929A5053484529 @default.
• W1978797929 hasAuthorship W1978797929A5088038013 @default.
• W1978797929 hasBestOaLocation W19787979291 @default.
• W1978797929 hasConcept C120665830 @default.
• W1978797929 hasConcept C121332964 @default.
• W1978797929 hasConcept C126322002 @default.
• W1978797929 hasConcept C164705383 @default.
• W1978797929 hasConcept C2778319312 @default.
• W1978797929 hasConcept C2779874844 @default.
• W1978797929 hasConcept C2780167933 @default.
• W1978797929 hasConcept C2908647359 @default.
• W1978797929 hasConcept C71924100 @default.
• W1978797929 hasConcept C84393581 @default.
• W1978797929 hasConcept C94915269 @default.
• W1978797929 hasConcept C99454951 @default.
• W1978797929 hasConceptScore W1978797929C120665830 @default.
• W1978797929 hasConceptScore W1978797929C121332964 @default.
• W1978797929 hasConceptScore W1978797929C126322002 @default.
• W1978797929 hasConceptScore W1978797929C164705383 @default.
• W1978797929 hasConceptScore W1978797929C2778319312 @default.
• W1978797929 hasConceptScore W1978797929C2779874844 @default.
• W1978797929 hasConceptScore W1978797929C2780167933 @default.
• W1978797929 hasConceptScore W1978797929C2908647359 @default.
• W1978797929 hasConceptScore W1978797929C71924100 @default.
• W1978797929 hasConceptScore W1978797929C84393581 @default.
• W1978797929 hasConceptScore W1978797929C94915269 @default.
• W1978797929 hasConceptScore W1978797929C99454951 @default.
• W1978797929 hasIssue "1" @default.
• W1978797929 hasLocation W19787979291 @default.
• W1978797929 hasLocation W19787979292 @default.
• W1978797929 hasLocation W19787979293 @default.
• W1978797929 hasOpenAccess W1978797929 @default.
• W1978797929 hasPrimaryLocation W19787979291 @default.
• W1978797929 hasRelatedWork W1991007679 @default.
• W1978797929 hasRelatedWork W2008851126 @default.
• W1978797929 hasRelatedWork W2043279994 @default.
• W1978797929 hasRelatedWork W2049397185 @default.
• W1978797929 hasRelatedWork W2119148367 @default.
• W1978797929 hasRelatedWork W2124960572 @default.
• W1978797929 hasRelatedWork W2159512267 @default.
• W1978797929 hasRelatedWork W2304633692 @default.
• W1978797929 hasRelatedWork W2399063111 @default.
• W1978797929 hasRelatedWork W2921741866 @default.
• W1978797929 hasVolume "16" @default.
• W1978797929 isParatext "false" @default.
• W1978797929 isRetracted "false" @default.
• W1978797929 magId "1978797929" @default.
• W1978797929 workType "article" @default.