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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978804937> ?p ?o ?g. }

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• W1978804937 abstract "The three-dimensional structure of the papain-leupeptin complex has been determined by X-ray crystallography to a resolution of 2.1 A (overall R-factor = 19.8%). The structure indicates that: (i) leupeptin contacts the S subsites of the papain active site and not the S' subsites; (ii) the 'carbonyl' carbon atom of the inhibitor is covalently bound by the Cys-25 sulphur atom of papain and is tetrahedrally coordinated; (iii) the 'carbonyl' oxygen atom of the inhibitor faces the oxyanion hole and makes hydrogen bond contacts with Gln-19 and Cys-25." @default.
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• W1978804937 date "1993-01-02" @default.
• W1978804937 modified "2023-09-25" @default.
• W1978804937 title "X-ray crystallographic structure of a papain-leupeptin complex" @default.
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• W1978804937 doi "https://doi.org/10.1016/0014-5793(93)81128-m" @default.
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