Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978804984> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1978804984 endingPage "277H" @default.
- W1978804984 startingPage "277H" @default.
- W1978804984 abstract "The renin-angiotensin system (RAS) plays a crucial role in the regulation of blood pressure (Laragh, 1995). Within the RAS, the physiological relevance of renin binding protein (RnBP) has been controversial for several years (Schmitz et al., 2000). Originally, RnBP was identified as a protein in the kidney that was capable of binding renin in renal homogenates giving rise to a complex designated high molecular weight renin (Takahashi et al., 1983). It was subsequently proposed that RnBP might act as an endogenous cellular renin inhibitor. Recent studies demonstrated that human RnBP is the enzyme N-acetyl-D-glucosamine (GlcNAc) 2-epimerase (Takahashi et al., 1999). Moreover, gene-targeting experiments in the mouse excluded a specific interaction between RnBP and renin in the kidney or in the circulating RAS of the mouse (Schmitz et al., 2000). So far, the gene encoding RnBP has been mapped on chromosome X in different mammals: Xq28 in human (van den Ouweland et al., 1994), X 29.53 cM in mouse (http:// www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=19703) and X in canine (Stoy et al., 1998). As mapping data for the rat homolog Renbp is still lacking, it is unclear whether this gene is located in blood pressure quantitative trait loci (QTL) termed BP/SP-2 and SS-X on rat chromosome X. BP/SP2 has been identified in an intercross between the stroke prone spontaneously hypertensive rat (SHRSP) and the normotensive Wistar-Kyoto (WKY) rat (Hilbert et al., 1991) and SS-X has been characterized in the Sabra hypertension-prone rat (Yagil et al., 1999). We therefore set out to test the chromosome location of Renbp by performing chromosomal mapping analysis in the rat using fluorescence in situ hybridization (FISH) and radiation hybrid (RH) mapping." @default.
- W1978804984 created "2016-06-24" @default.
- W1978804984 creator A5010898796 @default.
- W1978804984 creator A5017749990 @default.
- W1978804984 creator A5029567749 @default.
- W1978804984 creator A5067204984 @default.
- W1978804984 creator A5091895035 @default.
- W1978804984 date "2002-01-01" @default.
- W1978804984 modified "2023-10-05" @default.
- W1978804984 title "Assignment of the gene encoding renin binding protein <i>(Renbp)</i> to rat chromosome Xq37 by in situ hybridization and radiation hybrid mapping" @default.
- W1978804984 cites W1603949838 @default.
- W1978804984 cites W1958476774 @default.
- W1978804984 cites W1979881305 @default.
- W1978804984 cites W1983251645 @default.
- W1978804984 cites W1989713829 @default.
- W1978804984 cites W2002241222 @default.
- W1978804984 cites W2016203408 @default.
- W1978804984 cites W2041296030 @default.
- W1978804984 cites W2043299702 @default.
- W1978804984 cites W2104397421 @default.
- W1978804984 cites W2110134466 @default.
- W1978804984 cites W2145642186 @default.
- W1978804984 cites W2269233083 @default.
- W1978804984 cites W2409994215 @default.
- W1978804984 cites W2668407634 @default.
- W1978804984 cites W296277149 @default.
- W1978804984 doi "https://doi.org/10.1159/000066596" @default.
- W1978804984 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12866502" @default.
- W1978804984 hasPublicationYear "2002" @default.
- W1978804984 type Work @default.
- W1978804984 sameAs 1978804984 @default.
- W1978804984 citedByCount "1" @default.
- W1978804984 crossrefType "journal-article" @default.
- W1978804984 hasAuthorship W1978804984A5010898796 @default.
- W1978804984 hasAuthorship W1978804984A5017749990 @default.
- W1978804984 hasAuthorship W1978804984A5029567749 @default.
- W1978804984 hasAuthorship W1978804984A5067204984 @default.
- W1978804984 hasAuthorship W1978804984A5091895035 @default.
- W1978804984 hasBestOaLocation W19788049841 @default.
- W1978804984 hasConcept C104317684 @default.
- W1978804984 hasConcept C121332964 @default.
- W1978804984 hasConcept C122735190 @default.
- W1978804984 hasConcept C150194340 @default.
- W1978804984 hasConcept C153294291 @default.
- W1978804984 hasConcept C153911025 @default.
- W1978804984 hasConcept C2777714445 @default.
- W1978804984 hasConcept C2777822432 @default.
- W1978804984 hasConcept C30481170 @default.
- W1978804984 hasConcept C54355233 @default.
- W1978804984 hasConcept C81439078 @default.
- W1978804984 hasConcept C86803240 @default.
- W1978804984 hasConceptScore W1978804984C104317684 @default.
- W1978804984 hasConceptScore W1978804984C121332964 @default.
- W1978804984 hasConceptScore W1978804984C122735190 @default.
- W1978804984 hasConceptScore W1978804984C150194340 @default.
- W1978804984 hasConceptScore W1978804984C153294291 @default.
- W1978804984 hasConceptScore W1978804984C153911025 @default.
- W1978804984 hasConceptScore W1978804984C2777714445 @default.
- W1978804984 hasConceptScore W1978804984C2777822432 @default.
- W1978804984 hasConceptScore W1978804984C30481170 @default.
- W1978804984 hasConceptScore W1978804984C54355233 @default.
- W1978804984 hasConceptScore W1978804984C81439078 @default.
- W1978804984 hasConceptScore W1978804984C86803240 @default.
- W1978804984 hasIssue "3-4" @default.
- W1978804984 hasLocation W19788049841 @default.
- W1978804984 hasLocation W19788049842 @default.
- W1978804984 hasOpenAccess W1978804984 @default.
- W1978804984 hasPrimaryLocation W19788049841 @default.
- W1978804984 hasRelatedWork W1866648957 @default.
- W1978804984 hasRelatedWork W1974902510 @default.
- W1978804984 hasRelatedWork W2019904851 @default.
- W1978804984 hasRelatedWork W2050276160 @default.
- W1978804984 hasRelatedWork W2051823354 @default.
- W1978804984 hasRelatedWork W2076566836 @default.
- W1978804984 hasRelatedWork W2083776934 @default.
- W1978804984 hasRelatedWork W2087267442 @default.
- W1978804984 hasRelatedWork W2440143512 @default.
- W1978804984 hasRelatedWork W2779613469 @default.
- W1978804984 hasVolume "97" @default.
- W1978804984 isParatext "false" @default.
- W1978804984 isRetracted "false" @default.
- W1978804984 magId "1978804984" @default.
- W1978804984 workType "article" @default.