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- W1978806989 abstract "Long-term potentiation (LTP) in the auditory cortex was studied in slices obtained from adult rats. White matter stimulation produced field potentials in layers II/III, which were composed of two negative waves followed by a slow positivity. The second negative and third positive waves were blocked by a low Ca2+ (0.48 mM) medium or by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX, 10 μM), while the first negativity unchanged, d-2-amino-5-phosphonovalerate (d-AP5, 50 μM) showed no clear effect on the field potentials. Tetanic stimulation of the white matter produced potentiation in the second negativity, and the potentiation was maintained for at least 30 min. d-AP5 blocked this potentiation completely. These data indicate that LTP is evoked by activation of N-methyl-d-aspartate (NMDA) receptors in the auditory cortex of adult rats." @default.
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- W1978806989 date "1994-04-01" @default.
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- W1978806989 title "Long-term potentiation in the auditory cortex of adult rats" @default.
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- W1978806989 doi "https://doi.org/10.1016/0304-3940(94)90594-0" @default.
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