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- W1978812749 abstract "Four distinct types of cell contact occur between human platelets aggregated by adenosine diphosphate. These types make up a substantial proportion of the surface of aggregated platelets and do not intergrade. They have intercellular spaces of width 50 nm, 20 nm, 2–5 nm (gap contacts), and 0 (tight contacts), respectively. The 50-nm spaces are spanned by bridges that attach to stubs, abundant on the plasma membranes of circulating and aggregated platelets, and described here for the first time. In sectioned material, gap contacts and tight contacts resemble gap junctions and tight junctions. Freeze-fracture replicas, however, show that the gap and tight contacts and the 50-nm spaces are not associated with the presence of intramembranous specialisations typical of classical gap and tight junctions and desmosomes, respectively. Thus platelet aggregates possess three unique forms of cell contact and lack junctional complexes and desmosomes that occur in normal cellular tissues." @default.
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- W1978812749 date "1979-10-01" @default.
- W1978812749 modified "2023-09-28" @default.
- W1978812749 title "The fine structure of cell contacts in platelet aggregation" @default.
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- W1978812749 doi "https://doi.org/10.1016/s0022-5320(79)80040-4" @default.
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