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- W1978830767 abstract "Malignant gliomas are among the most devastating of cancers and are a major cause of mortality in a young population with a median survival time of 9 months following cytoreductive surgery, radiotherapy and chemotherapy. Recent studies showed that polyunsaturated fatty acids especially γ-linolenic acid (GLA) have selective tumoricidal action especially against malignant glioma cells both in vitro and in vivo. Limited open label clinical studies showed that intratumoral injection/infusion of GLA is safe and effective against malignant gliomas. In view of this, large-scale, double blind studies are needed to establish the usefulness of GLA in the treatment of malignant brain tumors." @default.
- W1978830767 created "2016-06-24" @default.
- W1978830767 creator A5003733759 @default.
- W1978830767 date "2004-06-01" @default.
- W1978830767 modified "2023-10-18" @default.
- W1978830767 title "From bench to the clinic: γ-linolenic acid therapy of human gliomas" @default.
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- W1978830767 doi "https://doi.org/10.1016/j.plefa.2003.12.001" @default.
- W1978830767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15120717" @default.
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