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- W1978840262 abstract "Borna disease virus infection of Lewis rats results in an immune-mediated disease associated with transient meningoencephalitis and persistent viral infection. In the acute phase of disease, perivascular immune cell infiltrates consisted of CD4 + and CD8 + T cells, macrophages and NK cells with peak expression of mRNAs encoding the cytokines IL1alpha, IL2, IL6, TNFalpha, and IFNgamma. In the chronic phase of disease, numbers of NK cells, B cells and activated microglia increased in the brain parenchyma with peak expression of IL4 mRNA. These data were consistent with a switch from a Th1-like, cellular immune response to a Th2-like, humoral immune response." @default.
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- W1978840262 date "1998-10-01" @default.
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- W1978840262 title "Evolution of the immune response in the central nervous system following infection with Borna disease virus" @default.
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- W1978840262 doi "https://doi.org/10.1016/s0165-5728(98)00076-9" @default.
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