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- W1978889676 abstract "Objective The goal of this study was to test the efficacy of paroxetine for primary insomnia in older adults. Methods Adults over age 55 with primary insomnia were randomly assigned to six weeks of double-blind treatment with paroxetine (N = 14) or placebo (N = 13). Outcome measures included persistence or resolution of insomnia; weekly diary measures of sleep quality, daytime alertness, and mood; and pre-/postpolysomnographic measures of sleep latency, wake time after sleep onset, and sleep efficiency. Results Although weekly diary-based measures showed improved subjective sleep quality, daytime alertness, and mood with paroxetine, the authors observed no effect on sleep efficiency or categorical response rates. Conclusion Paroxetine appears to be ineffective for treating primary insomnia in old age. The goal of this study was to test the efficacy of paroxetine for primary insomnia in older adults. Adults over age 55 with primary insomnia were randomly assigned to six weeks of double-blind treatment with paroxetine (N = 14) or placebo (N = 13). Outcome measures included persistence or resolution of insomnia; weekly diary measures of sleep quality, daytime alertness, and mood; and pre-/postpolysomnographic measures of sleep latency, wake time after sleep onset, and sleep efficiency. Although weekly diary-based measures showed improved subjective sleep quality, daytime alertness, and mood with paroxetine, the authors observed no effect on sleep efficiency or categorical response rates. Paroxetine appears to be ineffective for treating primary insomnia in old age." @default.
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- W1978889676 date "2006-09-01" @default.
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- W1978889676 title "Paroxetine Treatment of Primary Insomnia in Older Adults" @default.
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- W1978889676 doi "https://doi.org/10.1097/01.jgp.0000218327.21111.de" @default.
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