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- W1978892849 abstract "During the past decades, several cellular pathways have been discovered to be connected with the ageing process. These pathways, which either suppress or enhance the ageing process, include regulation of the insulin/growth hormone axis, pathways involved with caloric restriction, ROS metabolism and DNA repair. In this review, we will provide a comprehensive overview of cancer and/or accelerated ageing pathologies associated with defects in the multi-step nucleotide excision repair pathway. Moreover, we will discuss evidence suggesting that there is a causative link between transcription-coupled repair and ageing." @default.
- W1978892849 created "2016-06-24" @default.
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- W1978892849 date "2005-09-01" @default.
- W1978892849 modified "2023-10-01" @default.
- W1978892849 title "Transcription-coupled repair and premature ageing" @default.
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- W1978892849 doi "https://doi.org/10.1016/j.mrfmmm.2005.04.004" @default.
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