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• W1978892956 abstract "A new iridoid glycoside, 10-O-(4″-O-methylsuccinoyl)geniposide (7), and two new pyronane glycosides, jasminosides Q and R (13 and 14, resp.), along with nine known iridoid glycosides, 1–6 and 8–10, and two known pyronane glycosides, 11 and 12, were isolated from a MeOH extract of Gardeniae Fructus, the dried ripe fruit of Gardenia jasminoides (Rubiaceae). The structures of new compounds were elucidated on the basis of extensive spectroscopic analyses and comparison with literature. Upon evaluation of compounds 1–14 on the melanogenesis in B16 melanoma cells induced with α-melanocyte-stimulating hormone (α-MSH), three compounds, i.e., 6-O-p-coumaroylgeniposide (3), 7, and 6′-O-sinapoyljasminoside (12), exhibited inhibitory effects with 21.6–41.0 and 37.5–47.7% reduction of melanin content at 30 and 50 μM, respectively, with almost no toxicity to the cells (83.7–106.1% of cell viability at 50 μM)." @default.
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• W1978892956 date "2012-08-01" @default.
• W1978892956 modified "2023-09-25" @default.
• W1978892956 title "Melanogenesis Inhibitory Activity of Monoterpene Glycosides from Gardeniae Fructus" @default.
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• W1978892956 doi "https://doi.org/10.1002/cbdv.201200030" @default.
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