FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978894983> ?p ?o ?g. }

• W1978894983 endingPage "243" @default.
• W1978894983 startingPage "233" @default.
• W1978894983 abstract "Brain tumors can be advantageously treated with electron over photon radiation, by exploiting the rapid fall-off in dose with depth. This advantage could be further enhanced by utilizing multiple electron beams. However, in some beam configurations, wedged dose profiles would be necessary for the dose uniformity. Unlike photons, shaped pieces of material placed in electron beam severely degrade the energy, give additional scattering and, therefore, are suboptimal. The purpose of this study was to create wedged electron fields, using intensity modulation. The combination of electron wedges enables a more uniform coverage of brain tumors with a reduced dose to normal tissue.Intensity modulation was performed for 10 to 50 MeV electrons using a narrow scanning elementary beam of a racetrack Microtron accelerator, delivering radiation pulses with coordinates and intensities prescribed by a custom scan matrix. Dispensing more pulses (or longer pulses) within the field to increase the local dose, one can sharpen the penumbra at depth and generate wedged dose distributions of arbitrary angle as well as many other desired profiles. We modulated the electron beams, measured dose distributions using film in an anthropomorphic phantom, and compared the results with conventional techniques.Intensity modulation of electron beams decreases the 50-90% penumbra at depth by 40% and increases the flatness by 80%. Wedged profiles at depth can be created for any angle up to about 70 degrees, depending on the beam energy. Multiple modulated electron beams give smaller 20-70% but larger 70-100% isodose regions than photon beams.Electron beams can improve dose distributions in brain compared to the same number of photon beams, reducing the 20-70% isodoses region in normal tissue by 30%. Intensity modulation significantly improves the dose distribution from combined electron beams providing a sharper penumbra, better conformity, and reduced margin." @default.
• W1978894983 created "2016-06-24" @default.
• W1978894983 creator A5050136149 @default.
• W1978894983 creator A5065018773 @default.
• W1978894983 creator A5077600057 @default.
• W1978894983 date "1998-01-01" @default.
• W1978894983 modified "2023-09-24" @default.
• W1978894983 title "Electron Wedges for Radiation Therapy" @default.
• W1978894983 cites W1074931734 @default.
• W1978894983 cites W1965870899 @default.
• W1978894983 cites W1973532551 @default.
• W1978894983 cites W1973788926 @default.
• W1978894983 cites W1980444545 @default.
• W1978894983 cites W2004006404 @default.
• W1978894983 cites W2014447936 @default.
• W1978894983 cites W2025975670 @default.
• W1978894983 cites W2027486086 @default.
• W1978894983 cites W2028682705 @default.
• W1978894983 cites W2032267995 @default.
• W1978894983 cites W2033456044 @default.
• W1978894983 cites W2056680048 @default.
• W1978894983 cites W2061772583 @default.
• W1978894983 cites W2062784757 @default.
• W1978894983 cites W2063773281 @default.
• W1978894983 cites W2064081954 @default.
• W1978894983 cites W2065703470 @default.
• W1978894983 cites W2065862849 @default.
• W1978894983 cites W2093233871 @default.
• W1978894983 cites W2102195876 @default.
• W1978894983 cites W2111949143 @default.
• W1978894983 cites W2139738324 @default.
• W1978894983 cites W2141983610 @default.
• W1978894983 cites W2144644621 @default.
• W1978894983 cites W2171243706 @default.
• W1978894983 cites W2219418615 @default.
• W1978894983 cites W2744797417 @default.
• W1978894983 cites W3028092869 @default.
• W1978894983 cites W4237530851 @default.
• W1978894983 doi "https://doi.org/10.1016/s0360-3016(97)00565-8" @default.
• W1978894983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9422581" @default.
• W1978894983 hasPublicationYear "1998" @default.
• W1978894983 type Work @default.
• W1978894983 sameAs 1978894983 @default.
• W1978894983 citedByCount "8" @default.
• W1978894983 countsByYear W19788949832013 @default.
• W1978894983 countsByYear W19788949832016 @default.
• W1978894983 crossrefType "journal-article" @default.
• W1978894983 hasAuthorship W1978894983A5050136149 @default.
• W1978894983 hasAuthorship W1978894983A5065018773 @default.
• W1978894983 hasAuthorship W1978894983A5077600057 @default.
• W1978894983 hasBestOaLocation W19788949831 @default.
• W1978894983 hasConcept C104293457 @default.
• W1978894983 hasConcept C120665830 @default.
• W1978894983 hasConcept C121332964 @default.
• W1978894983 hasConcept C147120987 @default.
• W1978894983 hasConcept C153385146 @default.
• W1978894983 hasConcept C159317903 @default.
• W1978894983 hasConcept C164705383 @default.
• W1978894983 hasConcept C168834538 @default.
• W1978894983 hasConcept C180048950 @default.
• W1978894983 hasConcept C181401712 @default.
• W1978894983 hasConcept C184779094 @default.
• W1978894983 hasConcept C185544564 @default.
• W1978894983 hasConcept C26405456 @default.
• W1978894983 hasConcept C2778530986 @default.
• W1978894983 hasConcept C2779946633 @default.
• W1978894983 hasConcept C2780577055 @default.
• W1978894983 hasConcept C48925448 @default.
• W1978894983 hasConcept C541997718 @default.
• W1978894983 hasConcept C62520636 @default.
• W1978894983 hasConcept C71924100 @default.
• W1978894983 hasConcept C89631360 @default.
• W1978894983 hasConcept C95312477 @default.
• W1978894983 hasConcept C96834759 @default.
• W1978894983 hasConceptScore W1978894983C104293457 @default.
• W1978894983 hasConceptScore W1978894983C120665830 @default.
• W1978894983 hasConceptScore W1978894983C121332964 @default.
• W1978894983 hasConceptScore W1978894983C147120987 @default.
• W1978894983 hasConceptScore W1978894983C153385146 @default.
• W1978894983 hasConceptScore W1978894983C159317903 @default.
• W1978894983 hasConceptScore W1978894983C164705383 @default.
• W1978894983 hasConceptScore W1978894983C168834538 @default.
• W1978894983 hasConceptScore W1978894983C180048950 @default.
• W1978894983 hasConceptScore W1978894983C181401712 @default.
• W1978894983 hasConceptScore W1978894983C184779094 @default.
• W1978894983 hasConceptScore W1978894983C185544564 @default.
• W1978894983 hasConceptScore W1978894983C26405456 @default.
• W1978894983 hasConceptScore W1978894983C2778530986 @default.
• W1978894983 hasConceptScore W1978894983C2779946633 @default.
• W1978894983 hasConceptScore W1978894983C2780577055 @default.
• W1978894983 hasConceptScore W1978894983C48925448 @default.
• W1978894983 hasConceptScore W1978894983C541997718 @default.
• W1978894983 hasConceptScore W1978894983C62520636 @default.
• W1978894983 hasConceptScore W1978894983C71924100 @default.
• W1978894983 hasConceptScore W1978894983C89631360 @default.
• W1978894983 hasConceptScore W1978894983C95312477 @default.
• W1978894983 hasConceptScore W1978894983C96834759 @default.
• W1978894983 hasIssue "1" @default.

• next