FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978921714> ?p ?o ?g. }

• W1978921714 endingPage "3690" @default.
• W1978921714 startingPage "3675" @default.
• W1978921714 abstract "Lung cancer treatment is one of the most challenging fields in radiotherapy. The aim of the present study was to investigate what role helical tomotherapy (HT), a novel approach to the delivery of highly conformal dose distributions using intensity-modulated radiation fan beams, can play in difficult cases with large target volumes typical for many of these patients. Tomotherapy plans were developed for 15 patients with stage III inoperable non-small-cell lung cancer. While not necessarily clinically indicated, elective nodal irradiation was included for all cases to create the most challenging scenarios with large target volumes. A 2 cm margin was used around the gross tumour volume (GTV) to generate primary planning target volume (PTV2) and 1 cm margin around elective nodes for secondary planning target volume (PTV1) resulting in PTV1 volumes larger than 1000 cm3 in 13 of the 15 patients. Tomotherapy plans were created using an inverse treatment planning system (TomoTherapy Inc.) based on superposition/convolution dose calculation for a fan beam thickness of 25 mm and a pitch factor between 0.3 and 0.8. For comparison, plans were created using an intensity-modulated radiation therapy (IMRT) approach planned on a commercial treatment planning system (TheraplanPlus, Nucletron). Tomotherapy delivery times for the large target volumes were estimated to be between 4 and 19 min. Using a prescribed dose of 60 Gy to PTV2 and 46 Gy to PTV1, the mean lung dose was 23.8+/-4.6 Gy. A 'dose quality factor' was introduced to correlate the plan outcome with patient specific parameters. A good correlation was found between the quality of the HT plans and the IMRT plans with HT being slightly better in most cases. The overlap between lung and PTV was found to be a good indicator of plan quality for HT. The mean lung dose was found to increase by approximately 0.9 Gy per percent overlap volume. Helical tomotherapy planning resulted in highly conformal dose distributions. It allowed easy achievement of two different dose levels in the target simultaneously. As the overlap between PTV and lung volume is a major predictor of mean lung dose, future work will be directed to control of margins. Work is underway to investigate the possibility of breath-hold techniques for tomotherapy delivery to facilitate this aim." @default.
• W1978921714 created "2016-06-24" @default.
• W1978921714 creator A5015674303 @default.
• W1978921714 creator A5019768466 @default.
• W1978921714 creator A5025707855 @default.
• W1978921714 creator A5026893621 @default.
• W1978921714 creator A5029281527 @default.
• W1978921714 creator A5032441898 @default.
• W1978921714 creator A5038831861 @default.
• W1978921714 creator A5041494387 @default.
• W1978921714 creator A5047265985 @default.
• W1978921714 creator A5065708016 @default.
• W1978921714 creator A5031041959 @default.
• W1978921714 date "2004-07-31" @default.
• W1978921714 modified "2023-10-13" @default.
• W1978921714 title "Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy" @default.
• W1978921714 cites W1781834802 @default.
• W1978921714 cites W1974662382 @default.
• W1978921714 cites W1982794835 @default.
• W1978921714 cites W1984951715 @default.
• W1978921714 cites W1992228359 @default.
• W1978921714 cites W1992998054 @default.
• W1978921714 cites W1999273467 @default.
• W1978921714 cites W2005957375 @default.
• W1978921714 cites W2006297687 @default.
• W1978921714 cites W2009650722 @default.
• W1978921714 cites W2019570186 @default.
• W1978921714 cites W2028242201 @default.
• W1978921714 cites W2033290173 @default.
• W1978921714 cites W2036018628 @default.
• W1978921714 cites W2040437473 @default.
• W1978921714 cites W2051767374 @default.
• W1978921714 cites W2053683763 @default.
• W1978921714 cites W2071918875 @default.
• W1978921714 cites W2075161134 @default.
• W1978921714 cites W2078150892 @default.
• W1978921714 cites W2088829989 @default.
• W1978921714 cites W2097512974 @default.
• W1978921714 cites W2107367062 @default.
• W1978921714 cites W2119298887 @default.
• W1978921714 cites W2134393828 @default.
• W1978921714 cites W2138736341 @default.
• W1978921714 cites W2147714642 @default.
• W1978921714 cites W2155053061 @default.
• W1978921714 cites W2155422011 @default.
• W1978921714 cites W4236889319 @default.
• W1978921714 cites W4245850509 @default.
• W1978921714 doi "https://doi.org/10.1088/0031-9155/49/16/014" @default.
• W1978921714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15446797" @default.
• W1978921714 hasPublicationYear "2004" @default.
• W1978921714 type Work @default.
• W1978921714 sameAs 1978921714 @default.
• W1978921714 citedByCount "62" @default.
• W1978921714 countsByYear W19789217142012 @default.
• W1978921714 countsByYear W19789217142013 @default.
• W1978921714 countsByYear W19789217142014 @default.
• W1978921714 countsByYear W19789217142015 @default.
• W1978921714 countsByYear W19789217142016 @default.
• W1978921714 countsByYear W19789217142017 @default.
• W1978921714 countsByYear W19789217142018 @default.
• W1978921714 crossrefType "journal-article" @default.
• W1978921714 hasAuthorship W1978921714A5015674303 @default.
• W1978921714 hasAuthorship W1978921714A5019768466 @default.
• W1978921714 hasAuthorship W1978921714A5025707855 @default.
• W1978921714 hasAuthorship W1978921714A5026893621 @default.
• W1978921714 hasAuthorship W1978921714A5029281527 @default.
• W1978921714 hasAuthorship W1978921714A5031041959 @default.
• W1978921714 hasAuthorship W1978921714A5032441898 @default.
• W1978921714 hasAuthorship W1978921714A5038831861 @default.
• W1978921714 hasAuthorship W1978921714A5041494387 @default.
• W1978921714 hasAuthorship W1978921714A5047265985 @default.
• W1978921714 hasAuthorship W1978921714A5065708016 @default.
• W1978921714 hasConcept C119857082 @default.
• W1978921714 hasConcept C126838900 @default.
• W1978921714 hasConcept C143998085 @default.
• W1978921714 hasConcept C201645570 @default.
• W1978921714 hasConcept C2776256026 @default.
• W1978921714 hasConcept C2776713427 @default.
• W1978921714 hasConcept C2989005 @default.
• W1978921714 hasConcept C41008148 @default.
• W1978921714 hasConcept C509974204 @default.
• W1978921714 hasConcept C71924100 @default.
• W1978921714 hasConcept C75088862 @default.
• W1978921714 hasConcept C774472 @default.
• W1978921714 hasConceptScore W1978921714C119857082 @default.
• W1978921714 hasConceptScore W1978921714C126838900 @default.
• W1978921714 hasConceptScore W1978921714C143998085 @default.
• W1978921714 hasConceptScore W1978921714C201645570 @default.
• W1978921714 hasConceptScore W1978921714C2776256026 @default.
• W1978921714 hasConceptScore W1978921714C2776713427 @default.
• W1978921714 hasConceptScore W1978921714C2989005 @default.
• W1978921714 hasConceptScore W1978921714C41008148 @default.
• W1978921714 hasConceptScore W1978921714C509974204 @default.
• W1978921714 hasConceptScore W1978921714C71924100 @default.
• W1978921714 hasConceptScore W1978921714C75088862 @default.
• W1978921714 hasConceptScore W1978921714C774472 @default.
• W1978921714 hasIssue "16" @default.
• W1978921714 hasLocation W19789217141 @default.

• next