Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978921880> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1978921880 endingPage "417" @default.
- W1978921880 startingPage "397" @default.
- W1978921880 abstract "The hypothesis of chronically low brain serotonin levels as pathophysiologically linked to impulsive aggression has been around for several decades. Whereas the theory was initially based on indirect methods to probe serotonin function, our understanding of the neural mechanisms involved in impulsive aggression has progressed with recent advances in neuroimaging. The review integrates evidence based on data from several neuroimaging domains in humans. In vivo molecular neuroimaging findings demonstrate associations between impulsive aggression and high serotonin 1B and serotonin 4 receptor binding, high serotonin transporter levels, and low monoamine oxidase A levels, suggesting that low interstitial serotonin levels are a neurobiological risk factor for impulsive aggressive behavior. Imaging genetics suggests that serotonergic-related genetic polymorphisms associate with antisocial behavior, and some evidence indicates that the low-expressing monoamine oxidase A genotype specifically predisposes to impulsive aggression, which may be mediated by effects on corticolimbic function. Interventions that (presumably) alter serotonin levels have effects on brain activity within brain regions involved in impulsive aggression, notably the amygdala, dorsal striatum, anterior cingulate, insula, and prefrontal cortex. Based on these findings, we propose a model for the modulatory role of serotonin in impulsive aggression. Future studies should ensure that clinical features unique for impulsive aggression are appropriately assessed, and we propose investigations of knowledge gaps that can help confirm, refute, or modify our proposed model of impulsive aggression." @default.
- W1978921880 created "2016-06-24" @default.
- W1978921880 creator A5005996383 @default.
- W1978921880 date "1996-04-01" @default.
- W1978921880 modified "2023-09-24" @default.
- W1978921880 title "The Possessed as Dostoevskij's Homage to Gogol': An Essay in Traditional Criticism" @default.
- W1978921880 cites W1518238917 @default.
- W1978921880 cites W1593134364 @default.
- W1978921880 cites W1989394946 @default.
- W1978921880 cites W1997848791 @default.
- W1978921880 cites W2002137752 @default.
- W1978921880 cites W2015323707 @default.
- W1978921880 cites W2020434958 @default.
- W1978921880 cites W2063981668 @default.
- W1978921880 cites W2231605013 @default.
- W1978921880 cites W2322546290 @default.
- W1978921880 cites W2329231512 @default.
- W1978921880 cites W2334975334 @default.
- W1978921880 cites W2335459409 @default.
- W1978921880 cites W2499702953 @default.
- W1978921880 cites W2613616793 @default.
- W1978921880 cites W2788846193 @default.
- W1978921880 cites W2795767946 @default.
- W1978921880 doi "https://doi.org/10.1016/0304-3479(96)80518-7" @default.
- W1978921880 hasPublicationYear "1996" @default.
- W1978921880 type Work @default.
- W1978921880 sameAs 1978921880 @default.
- W1978921880 citedByCount "0" @default.
- W1978921880 crossrefType "journal-article" @default.
- W1978921880 hasAuthorship W1978921880A5005996383 @default.
- W1978921880 hasConcept C104996578 @default.
- W1978921880 hasConcept C114461151 @default.
- W1978921880 hasConcept C126322002 @default.
- W1978921880 hasConcept C138496976 @default.
- W1978921880 hasConcept C15744967 @default.
- W1978921880 hasConcept C169760540 @default.
- W1978921880 hasConcept C170493617 @default.
- W1978921880 hasConcept C2775864247 @default.
- W1978921880 hasConcept C2776743251 @default.
- W1978921880 hasConcept C2778897192 @default.
- W1978921880 hasConcept C2779144063 @default.
- W1978921880 hasConcept C2779448149 @default.
- W1978921880 hasConcept C2780062018 @default.
- W1978921880 hasConcept C37000724 @default.
- W1978921880 hasConcept C513476851 @default.
- W1978921880 hasConcept C52338299 @default.
- W1978921880 hasConcept C58693492 @default.
- W1978921880 hasConcept C71924100 @default.
- W1978921880 hasConceptScore W1978921880C104996578 @default.
- W1978921880 hasConceptScore W1978921880C114461151 @default.
- W1978921880 hasConceptScore W1978921880C126322002 @default.
- W1978921880 hasConceptScore W1978921880C138496976 @default.
- W1978921880 hasConceptScore W1978921880C15744967 @default.
- W1978921880 hasConceptScore W1978921880C169760540 @default.
- W1978921880 hasConceptScore W1978921880C170493617 @default.
- W1978921880 hasConceptScore W1978921880C2775864247 @default.
- W1978921880 hasConceptScore W1978921880C2776743251 @default.
- W1978921880 hasConceptScore W1978921880C2778897192 @default.
- W1978921880 hasConceptScore W1978921880C2779144063 @default.
- W1978921880 hasConceptScore W1978921880C2779448149 @default.
- W1978921880 hasConceptScore W1978921880C2780062018 @default.
- W1978921880 hasConceptScore W1978921880C37000724 @default.
- W1978921880 hasConceptScore W1978921880C513476851 @default.
- W1978921880 hasConceptScore W1978921880C52338299 @default.
- W1978921880 hasConceptScore W1978921880C58693492 @default.
- W1978921880 hasConceptScore W1978921880C71924100 @default.
- W1978921880 hasIssue "3" @default.
- W1978921880 hasLocation W19789218801 @default.
- W1978921880 hasOpenAccess W1978921880 @default.
- W1978921880 hasPrimaryLocation W19789218801 @default.
- W1978921880 hasRelatedWork W14427204 @default.
- W1978921880 hasRelatedWork W1982601163 @default.
- W1978921880 hasRelatedWork W2000442860 @default.
- W1978921880 hasRelatedWork W2042909643 @default.
- W1978921880 hasRelatedWork W2043763616 @default.
- W1978921880 hasRelatedWork W2110654827 @default.
- W1978921880 hasRelatedWork W2135422366 @default.
- W1978921880 hasRelatedWork W2142322501 @default.
- W1978921880 hasRelatedWork W241691304 @default.
- W1978921880 hasRelatedWork W2806186353 @default.
- W1978921880 hasVolume "39" @default.
- W1978921880 isParatext "false" @default.
- W1978921880 isRetracted "false" @default.
- W1978921880 magId "1978921880" @default.
- W1978921880 workType "article" @default.