FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978925093> ?p ?o ?g. }

• W1978925093 endingPage "157" @default.
• W1978925093 startingPage "148" @default.
• W1978925093 abstract "Acute administration of the stress hormone corticosterone enhances memory consolidation in a manner that is dependent upon the modulatory effects of the basolateral complex of the amygdala (BLA). Posttraining administration of corticosterone increases expression of the activity-regulated cytoskeletal-associated protein (Arc) in hippocampal synaptic-enriched fractions. Interference with hippocampal Arc expression impairs memory, suggesting that the corticosterone-induced increase in hippocampal Arc plays a role in the memory enhancing effect of the hormone. Blockade of β-adrenoceptors in the BLA attenuates the corticosterone-induced increase in hippocampal Arc expression and blocks corticosterone-induced memory enhancement. To determine whether posttraining corticosterone treatment affects Arc protein expression in synapses of other areas of the brain that are involved in memory processing, a memory-enhancing dose of corticosterone was administered to rats immediately after inhibitory avoidance training. As seen in the hippocampus, Arc protein expression was increased in synaptic fractions taken from the prelimbic region of the medial prefrontal cortex (mPFC). Blockade of Arc protein expression significantly impaired memory, indicating that the protein is necessary in the mPFC for long-term memory formation. To test the hypothesis that blockade of β-adrenoceptors in the BLA would block the effect of systemic corticosterone on memory and attenuate mPFC Arc expression, as it does in the hippocampus, posttraining intra-BLA microinfusions of the β-adrenoceptor antagonist propranolol were given concurrently with the systemic corticosterone injection. Although this treatment blocked corticosterone-induced memory enhancement, it increased corticosterone-induced Arc protein expression in mPFC synaptic fractions. These findings suggest that the BLA mediates stress hormone effects on memory by participating in the negative or positive regulation of corticosterone-induced synaptic plasticity in efferent brain regions." @default.
• W1978925093 created "2016-06-24" @default.
• W1978925093 creator A5022807876 @default.
• W1978925093 creator A5024900583 @default.
• W1978925093 creator A5028541191 @default.
• W1978925093 creator A5036370920 @default.
• W1978925093 date "2014-07-01" @default.
• W1978925093 modified "2023-09-23" @default.
• W1978925093 title "Corticosterone-induced enhancement of memory and synaptic Arc protein in the medial prefrontal cortex" @default.
• W1978925093 cites W1543075896 @default.
• W1978925093 cites W1577271808 @default.
• W1978925093 cites W1724698019 @default.
• W1978925093 cites W1965930842 @default.
• W1978925093 cites W1995549311 @default.
• W1978925093 cites W1997605652 @default.
• W1978925093 cites W2001254960 @default.
• W1978925093 cites W2001261239 @default.
• W1978925093 cites W2001682430 @default.
• W1978925093 cites W2002295425 @default.
• W1978925093 cites W2002364516 @default.
• W1978925093 cites W2006159608 @default.
• W1978925093 cites W2014543037 @default.
• W1978925093 cites W2017675687 @default.
• W1978925093 cites W2021282423 @default.
• W1978925093 cites W2024386053 @default.
• W1978925093 cites W2025267508 @default.
• W1978925093 cites W2026108792 @default.
• W1978925093 cites W2028385576 @default.
• W1978925093 cites W2031167848 @default.
• W1978925093 cites W2042020752 @default.
• W1978925093 cites W2043863702 @default.
• W1978925093 cites W2054817198 @default.
• W1978925093 cites W2055772777 @default.
• W1978925093 cites W2061396809 @default.
• W1978925093 cites W2063884007 @default.
• W1978925093 cites W2067330935 @default.
• W1978925093 cites W2071256705 @default.
• W1978925093 cites W2071287384 @default.
• W1978925093 cites W2074308026 @default.
• W1978925093 cites W2074802748 @default.
• W1978925093 cites W2078599937 @default.
• W1978925093 cites W2085425790 @default.
• W1978925093 cites W2093335984 @default.
• W1978925093 cites W2098925242 @default.
• W1978925093 cites W2107069925 @default.
• W1978925093 cites W2119781599 @default.
• W1978925093 cites W2119941783 @default.
• W1978925093 cites W2122988394 @default.
• W1978925093 cites W2129399226 @default.
• W1978925093 cites W2130497862 @default.
• W1978925093 cites W2130958493 @default.
• W1978925093 cites W2135490238 @default.
• W1978925093 cites W2141265667 @default.
• W1978925093 cites W2143860178 @default.
• W1978925093 cites W2152052452 @default.
• W1978925093 cites W2153304892 @default.
• W1978925093 cites W2155953918 @default.
• W1978925093 cites W2156322511 @default.
• W1978925093 cites W2160769038 @default.
• W1978925093 cites W2160783478 @default.
• W1978925093 cites W2167423431 @default.
• W1978925093 cites W2169371126 @default.
• W1978925093 cites W43339058 @default.
• W1978925093 doi "https://doi.org/10.1016/j.nlm.2014.02.007" @default.
• W1978925093 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4517463" @default.
• W1978925093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24603007" @default.
• W1978925093 hasPublicationYear "2014" @default.
• W1978925093 type Work @default.
• W1978925093 sameAs 1978925093 @default.
• W1978925093 citedByCount "21" @default.
• W1978925093 countsByYear W19789250932015 @default.
• W1978925093 countsByYear W19789250932016 @default.
• W1978925093 countsByYear W19789250932017 @default.
• W1978925093 countsByYear W19789250932018 @default.
• W1978925093 countsByYear W19789250932019 @default.
• W1978925093 countsByYear W19789250932020 @default.
• W1978925093 countsByYear W19789250932021 @default.
• W1978925093 countsByYear W19789250932022 @default.
• W1978925093 countsByYear W19789250932023 @default.
• W1978925093 crossrefType "journal-article" @default.
• W1978925093 hasAuthorship W1978925093A5022807876 @default.
• W1978925093 hasAuthorship W1978925093A5024900583 @default.
• W1978925093 hasAuthorship W1978925093A5028541191 @default.
• W1978925093 hasAuthorship W1978925093A5036370920 @default.
• W1978925093 hasBestOaLocation W19789250932 @default.
• W1978925093 hasConcept C126322002 @default.
• W1978925093 hasConcept C134018914 @default.
• W1978925093 hasConcept C148762608 @default.
• W1978925093 hasConcept C15744967 @default.
• W1978925093 hasConcept C169760540 @default.
• W1978925093 hasConcept C169900460 @default.
• W1978925093 hasConcept C170493617 @default.
• W1978925093 hasConcept C185592680 @default.
• W1978925093 hasConcept C2524010 @default.
• W1978925093 hasConcept C2778468042 @default.
• W1978925093 hasConcept C2779144063 @default.
• W1978925093 hasConcept C2779934784 @default.
• W1978925093 hasConcept C2780352252 @default.

• next