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- W1978945315 abstract "Epilepsy is a chronic neurologic condition, characterized by recurrent unprovoked seizures that affect over 2 million people in the USA [1] and 50 million worldwide [2]. Annual direct and indirect costs total at least US$12.5 billion in the USA [1]. Other costs to the individual with epilepsy, such as physical, psychological and social costs, are more difficult to quantify but no less important. Compared with the general population, mortality is increased 2–3 times from accidents, suicide, sudden unexplained death from epilepsy and other causes [3,4]. This issue of Therapy provides an update of epilepsy treatment, focusing on advances in seizure control and quality of life. Medications remain the mainstay of therapy. Approximately 20 drugs are currently available to treat epilepsy, 11 of these have been approved by the US FDA since 1993 [5]. Extended-release formulations, designed to limit adverse effects and improve compliance, have also become available for several widely used antiepileptic drugs. Drug selection relies on the classification of each patient’s epilepsy syndrome, seizure type, comorbidities, concurrent medications, adverse physical and neuropsychiatric medication effects, consideration of teratogenicity, cost, and other factors [5]." @default.
- W1978945315 created "2016-06-24" @default.
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- W1978945315 date "2010-09-01" @default.
- W1978945315 modified "2023-09-23" @default.
- W1978945315 title "Epilepsy therapy in 2010" @default.
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- W1978945315 doi "https://doi.org/10.2217/thy.10.61" @default.
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