Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978953823> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1978953823 abstract "MPP-production and uptake by dopaminergic terminals are critical steps in MPTP-induced Parkinson-like disorder. We reported evidence for a specific uptake of MPP by synaptic vesicles from mouse striatum. Its regional distribution suggests it as a marker of the dopamine vesicular carrier. We decided to further characterize such an MPP uptake. Tetrabenazine inhibits the dopamine uptake both in the striatum and in the cerebellum with similar Km values suggesting an identify of the vesicular carrier in these areas. On the contrary, 3H-MPP vesicular uptake had in the striatum a t1/2 of 60 sec, but was not detectable at any time in the cerebellum. Moreover, MPP inhibited the uptake of 3H-DA (Ki: 1.6 +/- 0.03 microM) and 3H-NE (Ki 2.6 +/- 0.01 microM) in the striatum but not in the cerebellum, even at molar concentration. These pharmacological data indicate that in nondopaminergic areas the monoamine carrier may be similar but not identical from that located in dopaminergic areas." @default.
- W1978953823 created "2016-06-24" @default.
- W1978953823 creator A5005312547 @default.
- W1978953823 creator A5024452017 @default.
- W1978953823 creator A5026078020 @default.
- W1978953823 creator A5061703839 @default.
- W1978953823 date "1996-10-01" @default.
- W1978953823 modified "2023-09-23" @default.
- W1978953823 title "Heterogeneity of monoaminergic vesicular carriers: Pharmacological evidence using MPP+ as a marker" @default.
- W1978953823 cites W1602098835 @default.
- W1978953823 cites W1684853394 @default.
- W1978953823 cites W1969378954 @default.
- W1978953823 cites W1980253852 @default.
- W1978953823 cites W1992333288 @default.
- W1978953823 cites W1994285288 @default.
- W1978953823 cites W1997339900 @default.
- W1978953823 cites W1998293863 @default.
- W1978953823 cites W2000956059 @default.
- W1978953823 cites W2004595816 @default.
- W1978953823 cites W2010595129 @default.
- W1978953823 cites W2041734419 @default.
- W1978953823 cites W2045855991 @default.
- W1978953823 cites W2063490039 @default.
- W1978953823 cites W2067488635 @default.
- W1978953823 cites W2069765052 @default.
- W1978953823 cites W2074631079 @default.
- W1978953823 cites W2074830850 @default.
- W1978953823 cites W2086170256 @default.
- W1978953823 cites W2086208850 @default.
- W1978953823 cites W2088002614 @default.
- W1978953823 cites W2093984096 @default.
- W1978953823 cites W2102131116 @default.
- W1978953823 cites W2103660407 @default.
- W1978953823 cites W2104831013 @default.
- W1978953823 cites W2111065594 @default.
- W1978953823 cites W2146889361 @default.
- W1978953823 cites W2000968344 @default.
- W1978953823 doi "https://doi.org/10.1016/s0024-3205(96)00506-1" @default.
- W1978953823 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8890944" @default.
- W1978953823 hasPublicationYear "1996" @default.
- W1978953823 type Work @default.
- W1978953823 sameAs 1978953823 @default.
- W1978953823 citedByCount "1" @default.
- W1978953823 crossrefType "journal-article" @default.
- W1978953823 hasAuthorship W1978953823A5005312547 @default.
- W1978953823 hasAuthorship W1978953823A5024452017 @default.
- W1978953823 hasAuthorship W1978953823A5026078020 @default.
- W1978953823 hasAuthorship W1978953823A5061703839 @default.
- W1978953823 hasConcept C12554922 @default.
- W1978953823 hasConcept C137183658 @default.
- W1978953823 hasConcept C169760540 @default.
- W1978953823 hasConcept C170493617 @default.
- W1978953823 hasConcept C185592680 @default.
- W1978953823 hasConcept C187714386 @default.
- W1978953823 hasConcept C2775864247 @default.
- W1978953823 hasConcept C2776284327 @default.
- W1978953823 hasConcept C2776291748 @default.
- W1978953823 hasConcept C2776755682 @default.
- W1978953823 hasConcept C2778406628 @default.
- W1978953823 hasConcept C2779652256 @default.
- W1978953823 hasConcept C2780062018 @default.
- W1978953823 hasConcept C42251903 @default.
- W1978953823 hasConcept C513476851 @default.
- W1978953823 hasConcept C55493867 @default.
- W1978953823 hasConcept C86803240 @default.
- W1978953823 hasConceptScore W1978953823C12554922 @default.
- W1978953823 hasConceptScore W1978953823C137183658 @default.
- W1978953823 hasConceptScore W1978953823C169760540 @default.
- W1978953823 hasConceptScore W1978953823C170493617 @default.
- W1978953823 hasConceptScore W1978953823C185592680 @default.
- W1978953823 hasConceptScore W1978953823C187714386 @default.
- W1978953823 hasConceptScore W1978953823C2775864247 @default.
- W1978953823 hasConceptScore W1978953823C2776284327 @default.
- W1978953823 hasConceptScore W1978953823C2776291748 @default.
- W1978953823 hasConceptScore W1978953823C2776755682 @default.
- W1978953823 hasConceptScore W1978953823C2778406628 @default.
- W1978953823 hasConceptScore W1978953823C2779652256 @default.
- W1978953823 hasConceptScore W1978953823C2780062018 @default.
- W1978953823 hasConceptScore W1978953823C42251903 @default.
- W1978953823 hasConceptScore W1978953823C513476851 @default.
- W1978953823 hasConceptScore W1978953823C55493867 @default.
- W1978953823 hasConceptScore W1978953823C86803240 @default.
- W1978953823 hasLocation W19789538231 @default.
- W1978953823 hasLocation W19789538232 @default.
- W1978953823 hasOpenAccess W1978953823 @default.
- W1978953823 hasPrimaryLocation W19789538231 @default.
- W1978953823 hasRelatedWork W1977833748 @default.
- W1978953823 hasRelatedWork W1978953823 @default.
- W1978953823 hasRelatedWork W1993220534 @default.
- W1978953823 hasRelatedWork W2013045923 @default.
- W1978953823 hasRelatedWork W2041631487 @default.
- W1978953823 hasRelatedWork W2051321877 @default.
- W1978953823 hasRelatedWork W2118207252 @default.
- W1978953823 hasRelatedWork W2170392605 @default.
- W1978953823 hasRelatedWork W300860852 @default.
- W1978953823 hasRelatedWork W3021027622 @default.
- W1978953823 isParatext "false" @default.
- W1978953823 isRetracted "false" @default.
- W1978953823 magId "1978953823" @default.
- W1978953823 workType "article" @default.