FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978978985> ?p ?o ?g. }

• W1978978985 endingPage "1352" @default.
• W1978978985 startingPage "1345" @default.
• W1978978985 abstract "Abstract We have previously shown that compatible organic osmolytes, such as betaine, myo -inositol and taurine, are part of the stress response of normal human keratinocytes (NHKs) to ultraviolet B (UVB) radiation. In this regard, we tested human HaCaT keratinocytes as a surrogate cell line for NHK. HaCaT cells osmo-dependently express mRNA specific for transport proteins for betaine (BGT-1), myo -inositol (SMIT) and taurine (TAUT). Compared to normoosmotic (305 mosmol/l) controls, which strongly constitutively expressed BGT-1 mRNA, strong induction of SMIT and TAUT mRNA as well as low induction of BGT-1 mRNA expression was observed between 3 and 9 h after hyperosmotic exposure (405 mosmol/l). This expression correlated with an increased osmolyte uptake. Conversely, hypoosmotic (205 mosmol/l) stimulation led to a significant efflux of osmolytes. Exposure to UVB (290–315 nm) radiation induced cell shrinkage which was followed by an upregulation of osmolyte transporter mRNA levels and osmolyte uptake. These results demonstrate that human HaCaT keratinocytes possess an osmolyte strategy including UVB-induced cell shrinkage and following increased osmolyte uptake. However, several differences in osmolyte transporter expression and uptake were noted between NHK and HaCaT cells, indicating that the use of HaCaT cells as a surrogate cell line for NHK has limitations." @default.
• W1978978985 created "2016-06-24" @default.
• W1978978985 creator A5008452332 @default.
• W1978978985 creator A5025247499 @default.
• W1978978985 creator A5036661625 @default.
• W1978978985 creator A5048003566 @default.
• W1978978985 date "2007-11-16" @default.
• W1978978985 modified "2023-09-28" @default.
• W1978978985 title "Ultraviolet B radiation induces cell shrinkage and increases osmolyte transporter mRNA expression and osmolyte uptake in HaCaT keratinocytes" @default.
• W1978978985 cites W1495980998 @default.
• W1978978985 cites W1564639611 @default.
• W1978978985 cites W1599200947 @default.
• W1978978985 cites W1811725048 @default.
• W1978978985 cites W1859174804 @default.
• W1978978985 cites W1949018849 @default.
• W1978978985 cites W1965096450 @default.
• W1978978985 cites W1966547087 @default.
• W1978978985 cites W1975405079 @default.
• W1978978985 cites W1975963491 @default.
• W1978978985 cites W1977039064 @default.
• W1978978985 cites W1981004086 @default.
• W1978978985 cites W1983015859 @default.
• W1978978985 cites W1985053841 @default.
• W1978978985 cites W1986115510 @default.
• W1978978985 cites W1992211938 @default.
• W1978978985 cites W1997787179 @default.
• W1978978985 cites W2006588066 @default.
• W1978978985 cites W2025297909 @default.
• W1978978985 cites W2025309953 @default.
• W1978978985 cites W2030570585 @default.
• W1978978985 cites W2032326394 @default.
• W1978978985 cites W2036009794 @default.
• W1978978985 cites W2055129444 @default.
• W1978978985 cites W2055660529 @default.
• W1978978985 cites W2065500785 @default.
• W1978978985 cites W2072437795 @default.
• W1978978985 cites W2074988901 @default.
• W1978978985 cites W2089333401 @default.
• W1978978985 cites W2102328708 @default.
• W1978978985 cites W2120521595 @default.
• W1978978985 cites W2122736696 @default.
• W1978978985 cites W2123856468 @default.
• W1978978985 cites W2140354392 @default.
• W1978978985 cites W2143464311 @default.
• W1978978985 cites W2177909750 @default.
• W1978978985 cites W2332697941 @default.
• W1978978985 cites W2337898325 @default.
• W1978978985 cites W2342744565 @default.
• W1978978985 doi "https://doi.org/10.1515/bc.2007.140" @default.
• W1978978985 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18020950" @default.
• W1978978985 hasPublicationYear "2007" @default.
• W1978978985 type Work @default.
• W1978978985 sameAs 1978978985 @default.
• W1978978985 citedByCount "16" @default.
• W1978978985 countsByYear W19789789852012 @default.
• W1978978985 countsByYear W19789789852013 @default.
• W1978978985 countsByYear W19789789852014 @default.
• W1978978985 countsByYear W19789789852015 @default.
• W1978978985 countsByYear W19789789852017 @default.
• W1978978985 countsByYear W19789789852018 @default.
• W1978978985 countsByYear W19789789852019 @default.
• W1978978985 countsByYear W19789789852020 @default.
• W1978978985 crossrefType "journal-article" @default.
• W1978978985 hasAuthorship W1978978985A5008452332 @default.
• W1978978985 hasAuthorship W1978978985A5025247499 @default.
• W1978978985 hasAuthorship W1978978985A5036661625 @default.
• W1978978985 hasAuthorship W1978978985A5048003566 @default.
• W1978978985 hasConcept C118995209 @default.
• W1978978985 hasConcept C127160389 @default.
• W1978978985 hasConcept C129900496 @default.
• W1978978985 hasConcept C153911025 @default.
• W1978978985 hasConcept C185592680 @default.
• W1978978985 hasConcept C202751555 @default.
• W1978978985 hasConcept C2777248517 @default.
• W1978978985 hasConcept C54355233 @default.
• W1978978985 hasConcept C55493867 @default.
• W1978978985 hasConcept C81885089 @default.
• W1978978985 hasConcept C86803240 @default.
• W1978978985 hasConcept C95444343 @default.
• W1978978985 hasConceptScore W1978978985C118995209 @default.
• W1978978985 hasConceptScore W1978978985C127160389 @default.
• W1978978985 hasConceptScore W1978978985C129900496 @default.
• W1978978985 hasConceptScore W1978978985C153911025 @default.
• W1978978985 hasConceptScore W1978978985C185592680 @default.
• W1978978985 hasConceptScore W1978978985C202751555 @default.
• W1978978985 hasConceptScore W1978978985C2777248517 @default.
• W1978978985 hasConceptScore W1978978985C54355233 @default.
• W1978978985 hasConceptScore W1978978985C55493867 @default.
• W1978978985 hasConceptScore W1978978985C81885089 @default.
• W1978978985 hasConceptScore W1978978985C86803240 @default.
• W1978978985 hasConceptScore W1978978985C95444343 @default.
• W1978978985 hasIssue "12" @default.
• W1978978985 hasLocation W19789789851 @default.
• W1978978985 hasLocation W19789789852 @default.
• W1978978985 hasOpenAccess W1978978985 @default.
• W1978978985 hasPrimaryLocation W19789789851 @default.
• W1978978985 hasRelatedWork W1966547087 @default.
• W1978978985 hasRelatedWork W1978978985 @default.

• next