Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978982826> ?p ?o ?g. }
- W1978982826 endingPage "228" @default.
- W1978982826 startingPage "219" @default.
- W1978982826 abstract "Alkyl hydroperoxide reductase 1 (Ahp1p) is a thioredoxin peroxidase of the peroxiredoxin family expressed by Saccharomyces cerevisiae. Recently, disruption of the AHP1 gene has shown that the gene is not essential for yeast growth on glucose medium but revealed a high sensitivity of null mutants to organic peroxides, suggesting that Ahp1p is an important enzyme implicated in oxidative stress protection in S. cerevisiae. To gain insight into antioxidant enzymatic mechanisms involved in cell protection against metal toxicity and glutathione depletion, we investigated the resistance of S. cerevisiae, in which the AHP1 gene was disrupted, against several metals and diethyl maleate, a glutathione depleting agent. We report that Ahp1p protects yeast against toxicity induced by copper, cobalt, chromium, arsenite, arsenate, mercury, zinc and diethyl maleate, suggesting that Ahp1p plays an important role in S. cerevisiae in the protection against metals possibly by reducing peroxides generated in cells by these compounds." @default.
- W1978982826 created "2016-06-24" @default.
- W1978982826 creator A5015188143 @default.
- W1978982826 creator A5081942719 @default.
- W1978982826 date "2002-10-01" @default.
- W1978982826 modified "2023-09-23" @default.
- W1978982826 title "Alkyl hydroperoxide reductase 1 protects Saccharomyces cerevisiae against metal ion toxicity and glutathione depletion" @default.
- W1978982826 cites W1501279037 @default.
- W1978982826 cites W1509725445 @default.
- W1978982826 cites W1531135506 @default.
- W1978982826 cites W1595716614 @default.
- W1978982826 cites W1873279410 @default.
- W1978982826 cites W1966728645 @default.
- W1978982826 cites W1969561648 @default.
- W1978982826 cites W1970519591 @default.
- W1978982826 cites W1971780336 @default.
- W1978982826 cites W1981553136 @default.
- W1978982826 cites W1983482333 @default.
- W1978982826 cites W1985131654 @default.
- W1978982826 cites W1991769222 @default.
- W1978982826 cites W1997720526 @default.
- W1978982826 cites W2016862957 @default.
- W1978982826 cites W2018066181 @default.
- W1978982826 cites W2036820051 @default.
- W1978982826 cites W2055212449 @default.
- W1978982826 cites W2070756319 @default.
- W1978982826 cites W2081663028 @default.
- W1978982826 cites W2081745487 @default.
- W1978982826 cites W2089062179 @default.
- W1978982826 cites W2091297151 @default.
- W1978982826 cites W2092463196 @default.
- W1978982826 cites W2102545348 @default.
- W1978982826 cites W2105348347 @default.
- W1978982826 cites W2105568529 @default.
- W1978982826 cites W2148377355 @default.
- W1978982826 cites W4250221563 @default.
- W1978982826 doi "https://doi.org/10.1016/s0378-4274(02)00280-1" @default.
- W1978982826 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12270680" @default.
- W1978982826 hasPublicationYear "2002" @default.
- W1978982826 type Work @default.
- W1978982826 sameAs 1978982826 @default.
- W1978982826 citedByCount "47" @default.
- W1978982826 countsByYear W19789828262012 @default.
- W1978982826 countsByYear W19789828262015 @default.
- W1978982826 countsByYear W19789828262018 @default.
- W1978982826 countsByYear W19789828262019 @default.
- W1978982826 countsByYear W19789828262022 @default.
- W1978982826 crossrefType "journal-article" @default.
- W1978982826 hasAuthorship W1978982826A5015188143 @default.
- W1978982826 hasAuthorship W1978982826A5081942719 @default.
- W1978982826 hasConcept C165069038 @default.
- W1978982826 hasConcept C178790620 @default.
- W1978982826 hasConcept C181199279 @default.
- W1978982826 hasConcept C185592680 @default.
- W1978982826 hasConcept C2776151105 @default.
- W1978982826 hasConcept C2776305511 @default.
- W1978982826 hasConcept C2777576037 @default.
- W1978982826 hasConcept C2777737464 @default.
- W1978982826 hasConcept C2778004101 @default.
- W1978982826 hasConcept C2778760513 @default.
- W1978982826 hasConcept C2779222958 @default.
- W1978982826 hasConcept C29730261 @default.
- W1978982826 hasConcept C502230775 @default.
- W1978982826 hasConcept C538909803 @default.
- W1978982826 hasConcept C55493867 @default.
- W1978982826 hasConceptScore W1978982826C165069038 @default.
- W1978982826 hasConceptScore W1978982826C178790620 @default.
- W1978982826 hasConceptScore W1978982826C181199279 @default.
- W1978982826 hasConceptScore W1978982826C185592680 @default.
- W1978982826 hasConceptScore W1978982826C2776151105 @default.
- W1978982826 hasConceptScore W1978982826C2776305511 @default.
- W1978982826 hasConceptScore W1978982826C2777576037 @default.
- W1978982826 hasConceptScore W1978982826C2777737464 @default.
- W1978982826 hasConceptScore W1978982826C2778004101 @default.
- W1978982826 hasConceptScore W1978982826C2778760513 @default.
- W1978982826 hasConceptScore W1978982826C2779222958 @default.
- W1978982826 hasConceptScore W1978982826C29730261 @default.
- W1978982826 hasConceptScore W1978982826C502230775 @default.
- W1978982826 hasConceptScore W1978982826C538909803 @default.
- W1978982826 hasConceptScore W1978982826C55493867 @default.
- W1978982826 hasIssue "3" @default.
- W1978982826 hasLocation W19789828261 @default.
- W1978982826 hasLocation W19789828262 @default.
- W1978982826 hasOpenAccess W1978982826 @default.
- W1978982826 hasPrimaryLocation W19789828261 @default.
- W1978982826 hasRelatedWork W1989911237 @default.
- W1978982826 hasRelatedWork W1992181654 @default.
- W1978982826 hasRelatedWork W2006354584 @default.
- W1978982826 hasRelatedWork W2009189569 @default.
- W1978982826 hasRelatedWork W2040757416 @default.
- W1978982826 hasRelatedWork W2554165198 @default.
- W1978982826 hasRelatedWork W2706317929 @default.
- W1978982826 hasRelatedWork W2751020903 @default.
- W1978982826 hasRelatedWork W3044858750 @default.
- W1978982826 hasRelatedWork W3200659209 @default.
- W1978982826 hasVolume "135" @default.
- W1978982826 isParatext "false" @default.
- W1978982826 isRetracted "false" @default.