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- W1979023908 abstract "Absolute levels and ratio of serotonergic compounds in food-related hypothalamic nuclei were determined with a Chromatographie method comparing for control (C) versus lean (L) versus obese (O) rats. In all three groups, a second parameter i.e., fasting (F) versus satiation (S) was superimposed on the body weight factor. Indoleamine levels failed to show statistical differences depending on the body weight and/or the nutritional status. A significant negative correlation between an index of the serotonin turnover, the 5-HIAA/5-HT ratio, and body weight was found for the paraventricular (PVN) nucleus in the C and L groups as well as for the lateral (LH) nucleus for the C and O groups. A positive correlation was found for the ventromedian (VMH) nucleus in the O group. These data suggest that the body weight factor is implicated in the central serotonergic regulation more than the feeding parameter." @default.
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- W1979023908 date "1989-03-01" @default.
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- W1979023908 title "Effects of food intake and body weight on a serotonergic turnover index in rat hypothalamus" @default.
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- W1979023908 doi "https://doi.org/10.1016/0361-9230(89)90106-8" @default.
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