Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979060462> ?p ?o ?g. }
- W1979060462 endingPage "188" @default.
- W1979060462 startingPage "180" @default.
- W1979060462 abstract "Inhibition of cellular respiration, oxidation of glutathione and induction of apoptosis have been reported in epithelial cells infected in vitro with influenza A virus (IAV). Here, the same biomarkers were investigated in vivo by assessing the lungs of BALB/c mice infected with IAV. Cellular respiration declined on day 3 and recovered on day 7 post-infection. For days 3-5, the rate (mean±SD) of respiration (µMO2min(-1)mg(-1)) in uninfected lungs was 0.103±0.021 (n=4) and in infected lungs was 0.076±0.025 (n=4, p=0.026). Relative cellular ATP (infected/uninfected) was 4.7 on day 2 and 1.07 on day 7. Intracellular caspase activity peaked on day 7. Cellular glutathione decreased by ≥10% on days 3-7. Lung pathology was prominent on day 3 and caspase-3 labeling was prominent on day 5. IAV infection was associated with suppression of cellular respiration, diminished glutathione, and induction of apoptosis. These functional biomarkers were associated with structural changes noted in infected mice." @default.
- W1979060462 created "2016-06-24" @default.
- W1979060462 creator A5016680398 @default.
- W1979060462 creator A5021945180 @default.
- W1979060462 creator A5028539861 @default.
- W1979060462 creator A5037640842 @default.
- W1979060462 creator A5037980313 @default.
- W1979060462 creator A5066589057 @default.
- W1979060462 creator A5067114391 @default.
- W1979060462 creator A5072145550 @default.
- W1979060462 creator A5083606632 @default.
- W1979060462 date "2013-11-01" @default.
- W1979060462 modified "2023-10-18" @default.
- W1979060462 title "Cellular bioenergetics, caspase activity and glutathione in murine lungs infected with influenza A virus" @default.
- W1979060462 cites W1483301458 @default.
- W1979060462 cites W1572583929 @default.
- W1979060462 cites W1598596229 @default.
- W1979060462 cites W1793304642 @default.
- W1979060462 cites W1967801053 @default.
- W1979060462 cites W1977219317 @default.
- W1979060462 cites W1977675750 @default.
- W1979060462 cites W1986173845 @default.
- W1979060462 cites W1986568749 @default.
- W1979060462 cites W1988530973 @default.
- W1979060462 cites W1992145913 @default.
- W1979060462 cites W1999440511 @default.
- W1979060462 cites W2001582473 @default.
- W1979060462 cites W2005812290 @default.
- W1979060462 cites W2006924461 @default.
- W1979060462 cites W2008217730 @default.
- W1979060462 cites W2023035638 @default.
- W1979060462 cites W2048502224 @default.
- W1979060462 cites W2054548447 @default.
- W1979060462 cites W2068353535 @default.
- W1979060462 cites W2075632360 @default.
- W1979060462 cites W2078242939 @default.
- W1979060462 cites W2080923534 @default.
- W1979060462 cites W2083180525 @default.
- W1979060462 cites W2097322191 @default.
- W1979060462 cites W2119611042 @default.
- W1979060462 cites W2121676840 @default.
- W1979060462 cites W2128677433 @default.
- W1979060462 cites W2157225192 @default.
- W1979060462 cites W2157879777 @default.
- W1979060462 cites W2161036637 @default.
- W1979060462 cites W2162435972 @default.
- W1979060462 cites W2168238670 @default.
- W1979060462 cites W2169905292 @default.
- W1979060462 cites W73347127 @default.
- W1979060462 doi "https://doi.org/10.1016/j.virol.2013.07.034" @default.
- W1979060462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24074580" @default.
- W1979060462 hasPublicationYear "2013" @default.
- W1979060462 type Work @default.
- W1979060462 sameAs 1979060462 @default.
- W1979060462 citedByCount "9" @default.
- W1979060462 countsByYear W19790604622014 @default.
- W1979060462 countsByYear W19790604622016 @default.
- W1979060462 countsByYear W19790604622017 @default.
- W1979060462 countsByYear W19790604622018 @default.
- W1979060462 countsByYear W19790604622020 @default.
- W1979060462 countsByYear W19790604622021 @default.
- W1979060462 crossrefType "journal-article" @default.
- W1979060462 hasAuthorship W1979060462A5016680398 @default.
- W1979060462 hasAuthorship W1979060462A5021945180 @default.
- W1979060462 hasAuthorship W1979060462A5028539861 @default.
- W1979060462 hasAuthorship W1979060462A5037640842 @default.
- W1979060462 hasAuthorship W1979060462A5037980313 @default.
- W1979060462 hasAuthorship W1979060462A5066589057 @default.
- W1979060462 hasAuthorship W1979060462A5067114391 @default.
- W1979060462 hasAuthorship W1979060462A5072145550 @default.
- W1979060462 hasAuthorship W1979060462A5083606632 @default.
- W1979060462 hasBestOaLocation W19790604621 @default.
- W1979060462 hasConcept C100206155 @default.
- W1979060462 hasConcept C105702510 @default.
- W1979060462 hasConcept C150903083 @default.
- W1979060462 hasConcept C181199279 @default.
- W1979060462 hasConcept C182215343 @default.
- W1979060462 hasConcept C190283241 @default.
- W1979060462 hasConcept C203014093 @default.
- W1979060462 hasConcept C207001950 @default.
- W1979060462 hasConcept C2522874641 @default.
- W1979060462 hasConcept C2777546802 @default.
- W1979060462 hasConcept C28859421 @default.
- W1979060462 hasConcept C538909803 @default.
- W1979060462 hasConcept C55493867 @default.
- W1979060462 hasConcept C79879829 @default.
- W1979060462 hasConcept C86803240 @default.
- W1979060462 hasConcept C95444343 @default.
- W1979060462 hasConceptScore W1979060462C100206155 @default.
- W1979060462 hasConceptScore W1979060462C105702510 @default.
- W1979060462 hasConceptScore W1979060462C150903083 @default.
- W1979060462 hasConceptScore W1979060462C181199279 @default.
- W1979060462 hasConceptScore W1979060462C182215343 @default.
- W1979060462 hasConceptScore W1979060462C190283241 @default.
- W1979060462 hasConceptScore W1979060462C203014093 @default.
- W1979060462 hasConceptScore W1979060462C207001950 @default.
- W1979060462 hasConceptScore W1979060462C2522874641 @default.
- W1979060462 hasConceptScore W1979060462C2777546802 @default.